公开(公告)号：US20210196840A1

公开(公告)日：2021-07-01

申请号：US17199122

申请日：2021-03-11

Applicant: BRACCO IMAGING S.P.A.

Inventor： Roberta NAPOLITANO ,  Luciano LATTUADA ,  Zsolt BARANYAI ,  Nicole GUIDOLIN ,  Giuseppe MARAZZI

IPC: A61K49/10 ,  C07F5/00

Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutamic glutaric acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.

公开(公告)号：US20240366802A1

公开(公告)日：2024-11-07

申请号：US18734341

申请日：2024-06-05

Applicant: BRACCO IMAGING S.P.A.

Inventor： Roberta NAPOLITANO ,  Luciano LATTUADA ,  Zsolt BARANYAI ,  Nicole GUIDOLIN ,  Giuseppe MARAZZI

IPC: A61K49/10 ,  C07D471/08 ,  C07F5/00

Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutamic acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.

公开(公告)号：US20200376145A1

公开(公告)日：2020-12-03

申请号：US16766619

申请日：2019-08-06

Applicant: BRACCO IMAGING S.P.A.

Inventor： Roberta NAPOLITANO ,  Luciano LATTUADA ,  Zsolt BARANYAI ,  Nicole GUIDOLIN ,  Giuseppe MARAZZI

IPC: A61K49/10 ,  C07F5/00

Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutamic acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.