公开(公告)号：US20160101104A1

公开(公告)日：2016-04-14

申请号：US14974248

申请日：2015-12-18

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： James H. Cook, II ,  Ivar M. McDonald ,  Dalton King ,  Richard E. Olson ,  Nenghui Wang ,  Christiana I. lwuagwu ,  F. Christopher Zusi ,  John E. Macor

IPC: A61K31/506

CPC classification number: A61K31/506 ,  A61K31/439 ,  C07D498/20 ,  C07D519/00

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.