公开(公告)号：US20230203039A1

公开(公告)日：2023-06-29

申请号：US17760309

申请日：2021-02-05

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Khehyong Ngu ,  Christopher Annunziato ,  John V. Duncia ,  Daniel Gardner

IPC: C07D471/22 ,  C07D498/22 ,  C07D487/22 ,  C07D519/00 ,  A61K45/06

CPC classification number: C07D471/22 ,  C07D498/22 ,  C07D487/22 ,  C07D519/00 ,  A61K45/06

Abstract: The present invention provides compounds of Formula (I) useful as inhibitors of PAD4, compositions thereof, and methods of treating PAD4-related disorders, (I) wherein ring A, A1, A2, A3, A4, Q, R1, R2, R3, R4, R5, and R6 along with other variables are as defined herein.