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公开(公告)号：US20180362619A1
公开(公告)日：2018-12-20
申请号：US16061646
申请日：2016-12-20
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Paul O. SHEPPARD , Henrik ANDERSEN , Xiang SHAO , Chetana RAO-NAIK , Arvind RAJPAL
Abstract: Variant antibodies having cysteine substitutions at selected positions in the Fc region can be conjugated via the thiol group of the substituted-in cysteine.
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