公开(公告)号：US20160376307A1

公开(公告)日：2016-12-29

申请号：US14903306

申请日：2014-07-10

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Kyoung S. KIM ,  Liping ZHANG ,  Erik M. STANG

IPC: C07K5/083 ,  A61K38/06 ,  A61K45/06

CPC classification number: C07K5/0806 ,  A61K38/00 ,  A61K38/06 ,  A61K45/06 ,  C07K14/4747 ,  C07K14/8139

Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.