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公开(公告)号：US20210283123A1
公开(公告)日：2021-09-16
申请号：US16328473
申请日：2017-08-25
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Liping ZHANG , Emily Charlotte CHERNEY , James Aaron BALOG , Xiao ZHU
IPC: A61K31/4709 , A61K39/395 , C07D413/08 , C07D401/08 , C07D417/08 , C07D417/14 , C07D413/14 , C07D413/12 , C07D417/12 , C07D401/12
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compound and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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公开(公告)号：US20190144417A1
公开(公告)日：2019-05-16
申请号：US16098245
申请日：2017-05-04
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： David K. WILLIAMS , Weifanq SHAN , Liping ZHANG , Emily Charlotte CHERNEY , James Aaron BALOG
IPC: C07D401/04 , A61P35/00 , C07D215/18 , A61K31/4709 , A61K31/47 , A61K31/496 , C07D401/06 , A61K31/444
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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公开(公告)号：US20190135758A1
公开(公告)日：2019-05-09
申请号：US16098288
申请日：2017-05-04
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Emily Charlotte CHERNEY , Weifang SHAN , Liping ZHANG , David K. WILLIAMS , Weiwei GUO , Audris HUANG , James Aaron BALOG
IPC: C07D215/18 , C07D401/04 , A61K31/4709 , A61P35/00 , A61K47/42
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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Patent Agency Ranking
公开(公告)号：US20160376307A1
公开(公告)日：2016-12-29
申请号：US14903306
申请日：2014-07-10
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Kyoung S. KIM , Liping ZHANG , Erik M. STANG
CPC classification number: C07K5/0806 , A61K38/00 , A61K38/06 , A61K45/06 , C07K14/4747 , C07K14/8139
Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
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公开(公告)号：US20210290613A1
公开(公告)日：2021-09-23
申请号：US16328449
申请日：2017-08-25
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Emily Charlotte CHERNEY , Weifang SHAN , Liping ZHANG , Susheel Jethanand NARA , Audris HUANG , James Aaron BALOG
IPC: A61K31/4709 , C07D401/08 , C07D491/056 , C07D471/04 , C07D417/12 , C07D401/12 , C07D413/12 , C07D487/04 , A61K31/517 , A61K31/5025 , A61K31/4375 , A61K39/395
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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公开(公告)号：US20190119216A1
公开(公告)日：2019-04-25
申请号：US16098260
申请日：2017-05-04
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Emily Charlotte CHERNEY , Liping ZHANG , David K. WILLIAMS , James Aaron BALOG
IPC: C07D215/18 , C07D401/04 , C07D215/233 , A61K31/4709 , A61K31/47 , A61K45/06 , A61P35/00
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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公开(公告)号：US20210206723A1
公开(公告)日：2021-07-08
申请号：US16754171
申请日：2018-10-08
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James Aaron BALOG , Emily Charlotte CHERNEY , Weifang SHAN , David K. WILLIAMS , Liping ZHANG
IPC: C07D215/46 , C07D215/14 , C07D401/12 , C07D401/04 , C07D401/06 , C07K16/28
Abstract: The present invention provides compounds of formula (I), formula (II) or formula (III), wherein all of the variables are as defined herein. These compounds are inhibitors of indoleamine 2,3-dioxygenase (IDO), which may be used as medicaments for the treatment of proliferative disorders, such as cancer, viral infections and/or autoimmune diseases.
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公开(公告)号：US20200095231A1
公开(公告)日：2020-03-26
申请号：US16612076
申请日：2018-05-10
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： James Aaron BALOG , Emily Charlotte CHERNEY , Liping ZHANG , Audris HUANG , Weifang SHAN , David K. WILLIAMS , Xiao ZHU , Weiwei GUO
IPC: C07D403/12 , C07D213/85 , C07D401/12 , C07D471/04
Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
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