Patent search ap:("BRISTOL-MYERS SQUIBB COMPANY") AND inv:"Patrick G. Holder" Page 1

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发明授权
Antibody comprising a glutamine-containing light chain C-terminal extension, conjugates thereof, and methods and uses 有权

公开(公告)号：US12290570B2

公开(公告)日：2025-05-06

申请号：US17297796

申请日：2019-11-25

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Pavel Strop , Chetana Rao-Naik , Xiaodi Deng , Paul O. Sheppard , Patrick G. Holder , Sayumi Yamazoe

IPC: A61K47/68 , C07K16/18

Abstract: An antibody has a glutamine-containing extension at the C-terminus of a light chain thereof, making it suitable for conjugation via transglutaminase-mediated transamidation.

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