专利检索 ap:("BRISTOL-MYERS SQUIBB COMPANY") AND inv:"Walter L JOHNSON" 第 1 页

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发明申请
1H-PYRAZOLO[4,3-d]PYRIMIDINE COMPOUNDS AS TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS 有权

公开(公告)号：US20230131192A1

公开(公告)日：2023-04-27

申请号：US17793155

申请日：2021-01-26

申请人： BRISTOL-MYERS SQUIBB COMPANY

发明人： Christine M. TARBY , Matthias BROEKEMA , Ashvinikumar V. GAVAI , Sanjeev GANGWAR , Naidu S. CHOWDARI , Walter L JOHNSON , Murugaiah ANDAPPAN MURUGAIAH SUBBAIAH

IPC分类号： C07D487/04 , A61K45/06

摘要： Compounds according to formula I are useful as agonists of Toll-like receptor 7 (TLR7). (I) Such compounds can be used in cancer treatment, especially in combination with an anti-cancer immunotherapy agent, or as a vaccine adjuvant.