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公开(公告)号：US09133219B2
公开(公告)日：2015-09-15
申请号：US14552853
申请日：2014-11-25
IPC分类号： C07D513/04 , C07D417/14 , C07D498/04 , C07D413/14 , C07D413/12 , C07D405/14 , C07D409/12 , C07D495/04 , C07D215/20 , C07D405/12 , C07D409/14 , C07D417/12 , C07D471/04 , C07D519/00 , C07D401/12
CPC分类号： C07D513/04 , C07D215/20 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D498/04 , C07D519/00
摘要： The antibacterial compound of formula I wherein X1, X3; X4 and X6, each independently of the others, represents a nitrogen atom or CR2, with the proviso that at least one of X1, X3; X4 and X6 represents a nitrogen atom; X2 represents C—H, C—(C1-C6alkyl), C—(C1-C6alkoxy), C-halogen, C—COOH; X5 represents C—H or C—(C1-C6alkyl), C-halogen; A1, A2, A3, R1 and R4 represent various substituents, G represents aryl or heteroaryl, which is unsubstituted or substituted which compounds show good activity against pathogenic bacteria.
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公开(公告)号：US08927542B2
公开(公告)日：2015-01-06
申请号：US14216486
申请日：2014-03-17
IPC分类号： C07D498/04 , A61K31/536 , A61K31/5365
CPC分类号： C07D513/04 , C07D215/20 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D498/04 , C07D519/00
摘要： The antibacterial compound of formula I wherein X1, X3; X4 and X6, each independently of the others, represents a nitrogen atom or CR2, with the proviso that at least one of X1, X3; X4 and X6 represents a nitrogen atom; X2 represents C—H, C—(C1-C6alkyl), C—(C1-C6alkoxy), C-halogen, C—COOH; X5 represents C—H or C—(C1-C6alkyl), C-halogen; A1, A2, A3, R1 and R4 represent various substituents, G represents aryl or heteroaryl, which is unsubstituted or substituted which compounds show good activity against pathogenic bacteria.
摘要翻译： 式I的抗菌化合物，其中X 1，X 3; X 4和X 6各自独立地表示氮原子或CR 2，条件是X 1，X 3; X4和X6表示氮原子; X代表C-H，C-（C 1 -C 6烷基），C-（C 1 -C 6烷氧基），C-卤素，C-COOH; X 5表示C-H或C-（C 1 -C 6烷基），C-卤素; A1，A2，A3，R1和R4表示各种取代基，G表示未取代或取代的芳基或杂芳基，哪种化合物对病原菌表现出良好的活性。
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公开(公告)号：US20150080373A1
公开(公告)日：2015-03-19
申请号：US14552853
申请日：2014-11-25
IPC分类号： C07D513/04 , C07D498/04 , C07D413/14 , C07D215/20 , C07D405/14 , C07D409/12 , C07D401/12 , C07D495/04 , C07D417/14 , C07D413/12
CPC分类号： C07D513/04 , C07D215/20 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D498/04 , C07D519/00
摘要： The antibacterial compound of formula I wherein X1, X3; X4 and X6, each independently of the others, represents a nitrogen atom or CR2, with the proviso that at least one of X1, X3; X4 and X6 represents a nitrogen atom; X2 represents C—H, C—(C1-C6alkyl), C—(C1-C6alkoxy), C-halogen, C—COOH; X5 represents C—H or C—(C1-C6alkyl), C-halogen; A1, A2, A3, R1 and R4 represent various substituents, G represents aryl or heteroaryl, which is unsubstituted or substituted which compounds show good activity against pathogenic bacteria.
摘要翻译： 式I的抗菌化合物，其中X 1，X 3; X 4和X 6各自独立地表示氮原子或CR 2，条件是X 1，X 3; X4和X6表示氮原子; X代表C-H，C-（C 1 -C 6烷基），C-（C 1 -C 6烷氧基），C-卤素，C-COOH; X 5表示C-H或C-（C 1 -C 6烷基），C-卤素; A1，A2，A3，R1和R4表示各种取代基，G表示未取代或取代的芳基或杂芳基，哪种化合物对病原菌表现出良好的活性。
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公开(公告)号：US09120822B2
公开(公告)日：2015-09-01
申请号：US14546589
申请日：2014-11-18
发明人： Berangere Gaucher, Jr. , Franck Hubert Danel , XiaoHu Tang , Tong Xie , Lin Xu
IPC分类号： C07D513/04 , C07D491/04 , C07D495/04 , C07D491/052 , C07D491/147 , C07D498/04 , C07D498/14
CPC分类号： C07D513/04 , C07D491/04 , C07D491/052 , C07D491/147 , C07D495/04 , C07D498/04 , C07D498/14
摘要： The present invention relates to antibacterial compounds of formula I: wherein all variable substituents are defined as described herein, which are useful for the treatment of bacterial infections.
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公开(公告)号：US20150072975A1
公开(公告)日：2015-03-12
申请号：US14546589
申请日：2014-11-18
发明人： Berangere Gaucher, JR. , Franck Hubert Danel , XiaoHu Tang , Tong Xie , Lin XU
IPC分类号： C07D513/04 , C07D491/147 , C07D498/04 , C07D498/14 , C07D491/052 , C07D495/04
CPC分类号： C07D513/04 , C07D491/04 , C07D491/052 , C07D491/147 , C07D495/04 , C07D498/04 , C07D498/14
摘要： The present invention relates to antibacterial compounds of formula I: wherein all variable substituents are defined as described herein, which are useful for the treatment of bacterial infections.
摘要翻译： 本发明涉及式I的抗菌化合物：其中所有可变取代基如本文所述定义，其可用于治疗细菌感染。
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公开(公告)号：US20140221348A1
公开(公告)日：2014-08-07
申请号：US14216486
申请日：2014-03-17
IPC分类号： C07D519/00 , C07D471/04 , C07D513/04 , C07D498/04 , C07D405/14 , C07D417/14 , C07D413/14
CPC分类号： C07D513/04 , C07D215/20 , C07D401/12 , C07D405/12 , C07D405/14 , C07D409/12 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D495/04 , C07D498/04 , C07D519/00
摘要： The antibacterial compound of formula I wherein X1, X3; X4 and X6, each independently of the others, represents a nitrogen atom or CR2, with the proviso that at least one of X1, X3; X4 and X6 represents a nitrogen atom; X2 represents C—H, C—(C1-C6alkyl), C—(C1-C6alkoxy), C-halogen, C—COOH; X5 represents C—H or C—(C1-C6alkyl), C-halogen; A1, A2, A3, R1 and R4 represent various substituents, G represents aryl or heteroaryl, which is unsubstituted or substituted which compounds show good activity against pathogenic bacteria.
摘要翻译： 式I的抗菌化合物，其中X 1，X 3; X 4和X 6各自独立地表示氮原子或CR 2，条件是X 1，X 3; X4和X6表示氮原子; X代表C-H，C-（C 1 -C 6烷基），C-（C 1 -C 6烷氧基），C-卤素，C-COOH; X 5表示C-H或C-（C 1 -C 6烷基），C-卤素; A1，A2，A3，R1和R4表示各种取代基，G表示未取代或取代的芳基或杂芳基，哪种化合物对病原菌表现出良好的活性。
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