公开(公告)号：US20180208937A1

公开(公告)日：2018-07-26

申请号：US15758429

申请日：2016-09-08

Applicant: Bayer CropScience Aktiengesellschaft ,  BAYER CROPSCIENCE LP

Inventor： Marc Linka ,  Fabien POREE ,  Bernd LABER ,  Gudrun LANGE ,  Jan TEBBE ,  Wayne COCO ,  Michael STRERATH ,  Ernst WEBER ,  Nikolaus PAWLOWSKI ,  Sandra GESKE ,  Heike BALVEN-ROSS ,  Nina WOBST ,  Christina THIES ,  Manuel DUBALD

IPC: C12N15/82 ,  C12N9/02

CPC classification number: C12N15/8274 ,  C12N9/0069 ,  C12Y113/11027

Abstract: In the present invention, HPPD polypeptides and plants containing them showing a full tolerance against one or more HPPD inhibitor herbicides belonging to various chemical classes are described.A set of mutant HPPD polypeptides have been designed which have either no or only a significantly reduced affinity to HPPD inhibitor herbicides and, at the same time, the rate of dissociation of the HPPD inhibitors of the mutant HPPD polypeptide is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors.In particular, isolated polynucleotides encoding mutant HPPD polypeptides conferring tolerance to HPPD inhibitor herbicides belonging to various chemical classes are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

公开(公告)号：US20170016018A1

公开(公告)日：2017-01-19

申请号：US15124861

申请日：2015-03-09

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT ,  BAYER CROPSCIENCE LP

Inventor： Fabien POREE ,  Bernd LABER ,  Gudrun LANGE ,  Manuel DUBALD ,  Roxanne ARMSTRONG

IPC: C12N15/82 ,  A01N43/713 ,  C12N9/02

CPC classification number: C12N15/8274 ,  A01N43/713 ,  C12N9/0069 ,  C12Y113/11001

Abstract: In the present invention, HPPD enzymes and plants containing them showing a full tolerance against several classes of HPPD-inhibitors are described.A set of HPPD enzymes have been designed which have either no or only a significantly reduced affinity to HPPD inhibitors and, at the same time, the rate of dissociation of the HPPD inhibitors of the enzyme is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors.In particular, isolated polynucleotides encoding HPPD inhibitor tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed.

Abstract translation: 特别地，提供了编码HPPD抑制剂耐受多肽的分离的多核苷酸。 另外，包括对应于多核苷酸的氨基酸序列。

公开(公告)号：US20160298129A1

公开(公告)日：2016-10-13

申请号：US15100810

申请日：2014-12-01

Applicant: BAYER CROPSCIENCE NV ,  BAYER CROPSCIENCE LP

Inventor： Rene RUITER ,  Rudiger HAIN ,  Gerhard JOHANN ,  Bernd LABER ,  Bart LAMBERT

IPC: C12N15/82 ,  C12N9/10 ,  A01N47/36 ,  A01N43/42 ,  A01N65/08 ,  A01N43/50 ,  A01N43/54 ,  A01N43/90 ,  A01H1/02 ,  A01N47/38

CPC classification number: C12N15/8274 ,  A01H1/02 ,  A01H5/10 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N43/90 ,  A01N47/36 ,  A01N47/38 ,  A01N65/08 ,  C12N9/1022 ,  C12N15/8261 ,  C12N15/8278 ,  C12Y202/01006

Abstract: The present invention relates to an ALS inhibitor herbicide tolerant crop plants, such as allotetraploid Brassica plants, such as B. napus plants, progeny and parts thereof comprising mutations in acetolactase genes.

Abstract translation: 本发明涉及一种ALS抑制剂除草剂耐受性作物植物，例如异源四倍体芸苔属植物，例如欧洲油菜植物，其后代及其部分含有乙酰乳激酶基因中的突变。

公开(公告)号：US20160208277A1

公开(公告)日：2016-07-21

申请号：US14913020

申请日：2014-08-20

Applicant: BAYER CROPSCIENCE NV ,  BAYER CROPSCIENCE LP

Inventor： Rene RUITER ,  Rudiger HAIN ,  Gerhard JOHANN ,  Bernd LABER

IPC: C12N15/82 ,  A01N37/30 ,  C12N9/10

CPC classification number: C12N15/8274 ,  A01N37/30 ,  C12N9/1022 ,  C12N15/8278 ,  C12Y202/01006

Abstract: The present invention relates to an ALS inhibitor herbicide tolerant polyploid plants, such as B. napus or B. juncea plants, progeny and parts thereof comprising mutations in all acetolactase genes.

Abstract translation: 本发明涉及一种ALS抑制剂除草剂耐受性多倍体植物，例如欧洲油菜（B. napus）或黑莓（B. juncea）植物，其后代及其部分包括所有乙酰乳糖酶基因中的突变。

公开(公告)号：US20160160232A1

公开(公告)日：2016-06-09

申请号：US14903745

申请日：2014-07-10

Applicant: BAYER CROPSCIENCE LP

Inventor： Rene RUITER ,  Rüdiger HAIN ,  Gerhard JOHANN ,  Bernd LABER

IPC: C12N15/82

CPC classification number: C12N15/8278 ,  A01H5/10 ,  A01N25/00 ,  A01N43/90 ,  A01N47/36 ,  A23L19/00 ,  C12N9/88 ,  C12N15/8274 ,  C12Y401/03 ,  A01N43/42 ,  A01N43/50 ,  A01N43/54 ,  A01N47/38

Abstract: The present invention relates to an ALS inhibitor herbicide tolerant polyploid plants, such as B. napus or B. juncea plants, progeny and parts thereof comprising a mutation of all acetolactase genes.

Abstract translation: 本发明涉及一种ALS抑制剂除草剂耐药性多倍体植物，例如欧洲油菜（B. napus）或黑莓（B. juncea）植物，其后代及其部分包含所有乙酰乳酸酶基因的突变。