公开(公告)号：US20190144874A1

公开(公告)日：2019-05-16

申请号：US16191964

申请日：2018-11-15

申请人： Bayer CropScience LP

发明人： Damian CURTIS ,  Benjamin L. GOLOMB ,  Dilara ALLY ,  Florencia A. FICARRA ,  Rauf SALAMZADE ,  Bjorn A. TRAAG

IPC分类号： C12N15/74 ,  C12N9/04 ,  C07K14/325 ,  C12N9/42 ,  C12N9/24 ,  A01N63/02

摘要： Signal sequences useful for targeting proteins and peptides to the surface of endospores produced by Paenibacillus family members and methods of using the same are provided. The display of heterologous molecules, such as peptides, polypeptides and other recombinant constructs, on the spore surface of Paenibacillus family members, using particular N-terminal targeting sequences and derivatives of the same, are also provided.

公开(公告)号：US20220002736A1

公开(公告)日：2022-01-06

申请号：US17294215

申请日：2019-11-15

申请人： Bayer CropScience LP

发明人： Benjamin L. GOLOMB ,  Florencia A. FICARRA ,  Rauf SALAMZADE ,  Damian CURTIS ,  Kyle TIPTON ,  Dilara ALLY

IPC分类号： C12N15/62 ,  C07K14/195 ,  A01N63/20

摘要： Signal sequences useful for targeting proteins and peptides to the surface of endospores produced by Brevibacillus, Lysinibacillus, or Viridibacillus family members and methods of using the same are provided. The display of heterologous molecules, such as peptides, polypeptides and other recombinant constructs, on the exosporium of Brevibacillus, Lysinibacillus, or Viridibacillus family members, using particular N-terminal targeting sequences and derivatives of the same, and likewise are provided.

公开(公告)号：US20210238610A1

公开(公告)日：2021-08-05

申请号：US17217952

申请日：2021-03-30

申请人： Bayer CropScience LP

发明人： Damian CURTIS ,  Benjamin L. GOLOMB ,  Dilara ALLY ,  Florencia A. FICARRA ,  Rauf SALAMZADE ,  Bjorn A. TRAAG

IPC分类号： C12N15/74 ,  C12N9/04 ,  C07K14/325 ,  C12N9/24 ,  C12N9/42 ,  C07K14/195 ,  C12N11/16 ,  C12N15/62 ,  C12N1/20 ,  C12N15/10 ,  A01N63/50

摘要： Signal sequences useful for targeting proteins and peptides to the surface of endospores produced by Paenibacillus family members and methods of using the same are provided. The display of heterologous molecules, such as peptides, polypeptides and other recombinant constructs, on the spore surface of Paenibacillus family members, using particular N-terminal targeting sequences and derivatives of the same, are also provided.