公开(公告)号：US09168249B2

公开(公告)日：2015-10-27

申请号：US14613367

申请日：2015-02-04

申请人： Bayer Intellectual Property GmbH

发明人： Kai Thede ,  Ingo Flamme ,  Felix Oehme ,  Jens-Kerim Ergüden ,  Friederike Stoll ,  Joachim Schuhmacher ,  Hanno Wild ,  Peter Kolkhof ,  Hartmut Beck ,  Jörg Keldenich ,  Metin Akbaba ,  Mario Jeske

IPC分类号： A61K31/4439 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04

CPC分类号： C07D487/04 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/497 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/55 ,  A61K31/551 ,  A61K45/06 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04

摘要： The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.

公开(公告)号：US08987261B2

公开(公告)日：2015-03-24

申请号：US13769513

申请日：2013-02-18

申请人： Bayer Intellectual Property GmbH

发明人： Kai Thede ,  Ingo Flamme ,  Felix Oehme ,  Jens-Kerim Ergüden ,  Friederike Stoll ,  Joachim Schuhmacher ,  Hanno Wild ,  Peter Kolkhof ,  Hartmut Beck ,  Jörg Keldenich ,  Metin Akbaba ,  Mario Jeske

IPC分类号： A61K31/5377 ,  C07D417/14 ,  C07D401/14 ,  C07D471/04 ,  C07D413/14 ,  C07D403/14

CPC分类号： C07D487/04 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/497 ,  A61K31/506 ,  A61K31/5377 ,  A61K31/55 ,  A61K31/551 ,  A61K45/06 ,  C07D401/14 ,  C07D403/14 ,  C07D413/14 ,  C07D417/14 ,  C07D471/04

摘要： The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.

摘要翻译： 本申请涉及新型取代的二氢吡喃酮衍生物，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病，特别是心血管和血液疾病和肾脏的药物的用途 疾病和促进伤口愈合。