公开(公告)号：US09962389B2

公开(公告)日：2018-05-08

申请号：US15488155

申请日：2017-04-14

申请人： Bayer Intellectual Property GmbH

发明人： Ulrich Lücking ,  Rolf Bohlmann ,  Arne Scholz ,  Gerhard Siemeister ,  Mark Jean Gnoth ,  Ulf Bömer ,  Dirk Kosemund ,  Philip Lienau ,  Gerd Rühter ,  Carsten Schultz-Fademrecht

IPC分类号： C07D251/44 ,  C07D251/42 ,  C07D251/22 ,  C07D251/16 ,  C07D401/12 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12 ,  C07C381/10 ,  A61K31/53 ,  A61P35/00 ,  C07D405/04 ,  C07B59/00

CPC分类号： A61K31/53 ,  C07B59/002 ,  C07B2200/05 ,  C07C381/10 ,  C07D251/16 ,  C07D251/22 ,  C07D251/42 ,  C07D251/44 ,  C07D401/12 ,  C07D405/04 ,  C07D405/12 ,  C07D413/12 ,  C07D417/12

摘要： The present invention relates to 4-aryl-N-phenyl-1,3,5-triazin-2-amines containing a sulfoximine group of general formula (I) or (Ia) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I) or (Ia).