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公开(公告)号：US10035818B2
公开(公告)日：2018-07-31
申请号：US15472476
申请日：2017-03-29
发明人： Ingo Flamme , Johannes Köbberling , Hans-Georg Lerchen , Nils Griebenow , Rudolf Schohe-Loop , Sven Wittrock , Maria Köllnberger , Frank Wunder , Gorden Redlich , Andreas Knorr , Julie Marley , Iain Pritchard
CPC分类号： C07K5/06017 , A61K9/007 , A61K38/22 , A61K45/06 , A61K47/60 , C07K5/02 , C07K5/06078 , C07K14/575
摘要： The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for producing medicaments for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders.
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公开(公告)号：US09649363B2
公开(公告)日：2017-05-16
申请号：US14986488
申请日：2015-12-31
发明人： Ingo Flamme , Johannes Köbberling , Hans-Georg Lerchen , Nils Griebenow , Rudolf Schohe-Loop , Sven Wittrock , Maria Köllnberger , Frank Wunder , Gorden Redlich , Andreas Knorr , Julie Marley , Iain Pritchard
CPC分类号： C07K5/06017 , A61K9/007 , A61K38/22 , A61K45/06 , A61K47/60 , C07K5/02 , C07K5/06078 , C07K14/575
摘要： The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for producing medicaments for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders.
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公开(公告)号：US09603936B2
公开(公告)日：2017-03-28
申请号：US14355568
申请日：2012-10-30
发明人： Ingo Flamme , Johannes Köbberling , Hans-Georg Lerchen , Nils Griebenow , Rudolf Schohe-Loop , Sven Wittrock , Maria Köllnberger , Frank Wunder , Gorden Redlich , Andreas Knorr , Julie Marley , Iain Pritchard
IPC分类号： A61K38/22 , A61K47/48 , C07K14/575
CPC分类号： C07K5/06017 , A61K9/007 , A61K38/22 , A61K45/06 , A61K47/60 , C07K5/02 , C07K5/06078 , C07K14/575
摘要： The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for producing medicaments for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders.
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公开(公告)号：US20160367636A1
公开(公告)日：2016-12-22
申请号：US14986488
申请日：2015-12-31
发明人： Ingo Flamme , Johannes Kobberling , Hans-Georg Lerchen , Nils Griebenow , Rudolf Schohe-Loop , Sven Wittrock , Maria Kollnberger , Frank Wunder , Gordon Redlich , Andreas Knorr , Julie Marley , Iain Pritchard
CPC分类号： C07K5/06017 , A61K9/007 , A61K38/22 , A61K45/06 , A61K47/60 , C07K5/02 , C07K5/06078 , C07K14/575
摘要： The invention relates to novel polyethylene glycol (PEG) based prodrug of Adrenomedullin, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for producing medicaments for treatment and/or prevention of diseases, especially of cardiovascular, edematous and/or inflammatory disorders.
摘要翻译： 本发明涉及基于新型聚乙二醇（PEG）的肾上腺髓质素前药，其制备方法及其用于治疗和/或预防疾病的用途及其用于制备用于治疗和/或预防疾病的药物的用途 ，特别是心血管，水肿和/或炎症性疾病。
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