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公开(公告)号：US20210053941A1
公开(公告)日：2021-02-25
申请号：US17009553
申请日：2020-09-01
发明人： Ulrich BOTHE , Holger SIEBENEICHER , Nicole SCHMIDT , Reinhard NUBBEMEYER , Ulf BÖMER , Judith GÜNTHER , Holger STEUBER , Martin LANGE , Christian STEGMANN , Andreas SUTTER , Alexandra RAUSCH , Christian FRIEDRICH , Peter HAUFF
IPC分类号： C07D401/12 , C07F7/18 , A61P19/02 , A61K31/4439 , C07D405/14
摘要： The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.
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公开(公告)号：US20200157073A1
公开(公告)日：2020-05-21
申请号：US16604157
申请日：2018-04-04
发明人： Hartmut BECK , Raimund KAST , Mark MEININGHAUS , Chantal FUERSTNER , Timo STELLFELD , Clemens-Jeremias VON BUEHLER , Lisa DIETZ , Michaela BAIRLEIN , Johanna ANLAHR , Hannah JOERISSEN , Peter HAUFF , Joerg MUELLER , Karoline DROEBNER , Jens NAGEL
IPC分类号： C07D401/04 , A61P11/00 , A61P1/16 , A61P13/12 , C07D215/50 , C07D413/04 , C07D417/04
摘要： The present application relates to novel substituted N-arylethyl-2-aminoquinoline-4-carboxamide derivatives, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of fibrotic and inflammatory disorders.
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公开(公告)号：US20170349570A1
公开(公告)日：2017-12-07
申请号：US15529996
申请日：2015-11-25
发明人： Ulrich BOTHE , Holger SIEBENEICHER , Nicole SCHMIDT , Reinhard NUBBEMEYER , Ulf BÖMER , Judith GÜNTHER , Holger STEUBER , Martin LANGE , Christian STEGMANN , Andreas SUTTER , Alexandra RAUSCH , Christian FRIEDRICH , Peter HAUFF
IPC分类号： C07D401/12 , C07F7/18 , C07D405/14
CPC分类号： C07D401/12 , C07D405/14 , C07F7/1804
摘要： The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.
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公开(公告)号：US20220388982A1
公开(公告)日：2022-12-08
申请号：US17869674
申请日：2022-07-20
发明人： Ulrich BOTHE , Holger SIEBENEICHER , Nicole SCHMIDT , Reinhard NUBBEMEYER , Ulf BÖMER , Judith GÜNTHER , Holger STEUBER , Martin LANGE , Christian STEGMANN , Andreas SUTTER , Alexandra RAUSCH , Christian FRIEDRICH , Peter HAUFF
IPC分类号： C07D401/12 , C07F7/18 , A61P19/02 , A61K31/4439 , C07D405/14
摘要： The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.
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公开(公告)号：US20230174508A1
公开(公告)日：2023-06-08
申请号：US17869673
申请日：2022-07-20
发明人： Ulrich BOTHE , Holger SIEBENEICHER , Nicole SCHMIDT , Reinhard NUBBEMEYER , Ulf BÖMER , Judith GÜNTHER , Holger STEUBER , Martin LANGE , Christian STEGMANN , Andreas SUTTER , Alexandra RAUSCH , Christian FRIEDRICH , Peter HAUFF
IPC分类号： C07D401/12 , C07F7/18 , A61P19/02 , A61K31/4439 , C07D405/14
CPC分类号： C07D401/12 , C07F7/1804 , A61P19/02 , A61K31/4439 , C07D405/14
摘要： The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.
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公开(公告)号：US20190233395A1
公开(公告)日：2019-08-01
申请号：US16377025
申请日：2019-04-05
发明人： Ulrich BOTHE , Holger SIEBENEICHER , Nicole SCHMIDT , Reinhard NUBBEMEYER , Ulf BÖMER , Judith GÜNTHER , Holger STEUBER , Martin LANGE , Christian STEGMANN , Andreas SUTTER , Alexandra RAUSCH , Christian FRIEDRICH , Peter HAUFF
IPC分类号： C07D401/12 , C07F7/18 , A61P19/02 , A61K31/4439 , C07D405/14
摘要： The present application relates to novel substituted indazoles, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of endometriosis and endometriosis-associated pain and other endometriosis-associated symptoms such as dysmenorrhoea, dyspareunia, dysuria and dyschezia, of lymphoma, rheumatoid arthritis, spondyloarthritis (especially psoriatic spondyloarthritis and Bekhterev's disease), lupus erythematosus, multiple sclerosis, macular degeneration, COPD, gout, fatty liver disorders, insulin resistance, neoplastic disorders and psoriasis.
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