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公开(公告)号：US20090220493A1
公开(公告)日：2009-09-03
申请号：US11981715
申请日：2007-10-31
申请人： Beatrice Leveugle , Ragupathy Madiyalakan , Antoine A. Noujaim , Birgit C. Schultes , Bruce Darryl Hirsche
发明人： Beatrice Leveugle , Ragupathy Madiyalakan , Antoine A. Noujaim , Birgit C. Schultes , Bruce Darryl Hirsche
IPC分类号： A61K39/395 , A61P35/00 , C07K16/42
CPC分类号： C07K16/4208 , A61K39/00 , A61K2039/505 , C07K16/40
摘要： The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen.
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公开(公告)号：US07579445B2
公开(公告)日：2009-08-25
申请号：US10966789
申请日：2004-10-14
IPC分类号： C07K16/00
CPC分类号： C07K16/4208 , A61K39/00 , A61K2039/505 , C07K16/40
摘要： The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen.
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公开(公告)号：US07361346B1
公开(公告)日：2008-04-22
申请号：US09152698
申请日：1998-09-02
申请人： Ragupathy Madiyalakan , Antoine A. Noujaim , Richard P. Baum , Birgit Schultes , Beatrice Leveugle , Fernando Kreutz
发明人： Ragupathy Madiyalakan , Antoine A. Noujaim , Richard P. Baum , Birgit Schultes , Beatrice Leveugle , Fernando Kreutz
IPC分类号： A61K39/00 , A61K39/385
CPC分类号： C07K16/4266 , A61K2039/505 , C07K2317/732 , C07K2317/734
摘要： The invention provides a method for stimulating the production of antibodies to a cryptic epitope on a soluble antigen by administering to a patient having such a cryptic epitope a binding agent that binds to the soluble antigen and forming a complex between the binding agent and the soluble antigen, wherein the cryptic epitope is exposed and the patient generates antibodies that bind to the cryptic epitope.
摘要翻译： 本发明提供了一种通过向具有这样的隐性表位的患者施用结合于可溶性抗原并在结合剂和可溶性抗原之间形成复合物的结合剂来刺激对可溶性抗原上的隐性表位产生抗体的方法 ，其中所述隐性表位被暴露，并且所述患者产生结合所述隐性表位的抗体。
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4.发明授权Reagents and methods for inducing an immune response to prostate specific antigen 有权用于诱导对前列腺特异性抗原的免疫应答的试剂和方法公开(公告)号：US06881405B2
公开(公告)日：2005-04-19
申请号：US09332866
申请日：1999-06-15
IPC分类号： A61K39/395 , A61K39/00 , A61K39/385 , A61P13/08 , A61P15/00 , A61P35/00 , C07K16/40 , C07K16/42
CPC分类号： C07K16/4208 , A61K39/00 , A61K2039/505 , C07K16/40
摘要： The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen.
摘要翻译： 本发明是用于治疗前列腺癌的装置和方法，并且涉及施用与前列腺抗原特异性结合的抗体。
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公开(公告)号：US20050202018A1
公开(公告)日：2005-09-15
申请号：US10966789
申请日：2004-10-14
IPC分类号： A61K39/395 , A61K39/00 , A61K39/385 , A61P13/08 , A61P15/00 , A61P35/00 , C07K16/40 , C07K16/42
CPC分类号： C07K16/4208 , A61K39/00 , A61K2039/505 , C07K16/40
摘要： The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen.
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