公开(公告)号：US06773390B2

公开(公告)日：2004-08-10

申请号：US10102085

申请日：2002-03-20

Applicant: Benjamin David McDaniel

Inventor： Benjamin David McDaniel

IPC: A61N500

CPC classification number: A61N5/1002 ,  A61N2005/1025

Abstract: A radioactive source ribbon assembly may be reusably utilized in conjunction with a delivery sheath or catheter for delivering therapeutic dosages of ionizing radiation to various anatomical regions. The radioactive source ribbon assembly comprises an outer jacket formed from or coated with a lubricious coating for insertion into the delivery sheath or catheter. The assembly also comprises a radiation resistant sleeve formed from a braided structure which encapsulates a radioactive source and core. The braided structure is the primary axial load bearing member of the assembly and functions as such without sacrificing assembly flexibility.

Abstract translation: 放射源带组件可以与输送护套或导管结合使用，以将治疗剂量的电离辐射递送到各种解剖区域。 放射源带组件包括由用于插入输送鞘或导管的润滑涂层形成或涂覆的外护套。 组件还包括由封装放射源和芯的编织结构形成的防辐射套筒。 编织结构是组件的主要轴向承载构件，并且在不牺牲组装灵活性的情况下起作用。

公开(公告)号：US06497646B1

公开(公告)日：2002-12-24

申请号：US09808477

申请日：2001-03-14

Applicant: Roberto Candelaria ,  Benjamin David McDaniel

Inventor： Roberto Candelaria ,  Benjamin David McDaniel

IPC: A61N500

CPC classification number: A61N5/1002 ,  A61N2005/1025

Abstract: A unidummy intravascular radiotherapy source ribbon assembly is utilized to properly align radioactive seeds in a radioactive intravascular radiotherapy source ribbon assembly to control the dose rate profile such that only the proper tissue is irradiated. The source ribbon assembly includes a core comprising one or more sections having a first radiopacity and one or more sections having a second radiopacity.

Abstract translation: 利用单一的血管内放射治疗源带组件来适当地对准放射性血管内放射治疗源带组件中的放射性种子以控制剂量率分布，从而仅照射适当的组织。 源带组件包括包括具有第一不透射线的一个或多个部分的芯体和具有第二射线不透性的一个或多个部分。

公开(公告)号：US20080249595A1

公开(公告)日：2008-10-09

申请号：US11696257

申请日：2007-04-04

Applicant: Benjamin David McDaniel

Inventor： Benjamin David McDaniel

IPC: A61N1/05

CPC classification number: A61B18/1492 ,  A61B2018/00148 ,  A61B2018/00702 ,  A61B2018/00791

Abstract: An EP catheter includes a tip electrode having a core primarily comprised of copper with an outer layer of a biocompatible metal disposed thereon exhibits appropriate electrical and thermal conduction characteristics while being cost-effective to produce. Alternatively, an inner layer of a biocompatible metal is disposed on the inside of the primarily copper core. Such a tip electrode may also be provided with irrigation lumens. Such a tip electrode could be manufactured from sheets of metal that upon extrusion would comprise the outer layer, core and optional inner layer respectively.

Abstract translation: EP导管包括尖端电极，其具有主要由铜组成的芯，其上布置有生物相容性金属的外层，其具有适当的电和热传导特性，同时具有生产成本效益。 或者，生物相容性金属的内层设置在主要铜芯的内侧。 这样的尖端电极也可以设置有冲洗腔。 这种尖端电极可以由金属片制成，其在挤出时将分别包括外层，芯和任选的内层。

公开(公告)号：US06800055B2

公开(公告)日：2004-10-05

申请号：US09790122

申请日：2001-02-21

Applicant: Howard Ira Amols ,  Timothy Charles Kiorpes ,  Benjamin David McDaniel ,  Michael Dennis O'Hara

Inventor： Howard Ira Amols ,  Timothy Charles Kiorpes ,  Benjamin David McDaniel ,  Michael Dennis O'Hara

IPC: A61M3600

CPC classification number: A61N5/1002 ,  A61N2005/1024

Abstract: A low attenuation radioactive seed utilizing a core having a fluted or non-circular cross section is utilized for increasing the dose rate, decreasing the dwell times and improving the clinical outcomes by increasing the dose consistency throughout the treatment zone. The fluted or non-circular cross section core would increase the surface area for the deposition of the radioactive substance thereby increasing the therapeutic efficacy of the seed. In addition, the fluted or non-circular cross section may be designed in a manner to reduce photon emission attenuation by reducing the distance an inwardly directed photon would have to travel to traverse the core.

Abstract translation: 使用利用具有槽纹或非圆形横截面的芯的低衰减放射性种子来增加剂量率，减少停留时间并通过增加整个处理区域的剂量一致性来改善临床结果。 带槽或非圆形截面的芯将增加用于放射性物质沉积的表面积，从而提高种子的治疗功效。 此外，带槽纹或非圆形横截面可以以通过减小向内指向的光子将不得不行进穿过芯部的距离来减少光子发射衰减的方式设计。

公开(公告)号：US09089339B2

公开(公告)日：2015-07-28

申请号：US11696257

申请日：2007-04-04

Applicant: Benjamin David McDaniel

Inventor： Benjamin David McDaniel

IPC: A61B18/14 ,  A61B18/00

CPC classification number: A61B18/1492 ,  A61B2018/00148 ,  A61B2018/00702 ,  A61B2018/00791

Abstract: An EP catheter includes a tip electrode having a core primarily comprised of copper with an outer layer of a biocompatible metal disposed thereon exhibits appropriate electrical and thermal conduction characteristics while being cost-effective to produce. Alternatively, an inner layer of a biocompatible metal is disposed on the inside of the primarily copper core. Such a tip electrode may also be provided with irrigation lumens. Such a tip electrode could be manufactured from sheets of metal that upon extrusion would comprise the outer layer, core and optional inner layer respectively.

Abstract translation: EP导管包括尖端电极，其具有主要由铜组成的芯，其上布置有生物相容性金属的外层，其具有适当的电和热传导特性，同时具有生产成本效益。 或者，生物相容性金属的内层设置在主要铜芯的内侧。 这样的尖端电极也可以设置有冲洗腔。 这种尖端电极可以由金属片制成，其在挤出时将分别包括外层，芯和任选的内层。

公开(公告)号：US20080147046A1

公开(公告)日：2008-06-19

申请号：US11612838

申请日：2006-12-19

Applicant: Benjamin David McDaniel

Inventor： Benjamin David McDaniel

IPC: A61M25/14

CPC classification number: A61M25/0147 ,  A61M25/0043 ,  A61M25/0045 ,  A61M25/0054 ,  A61M25/0138 ,  A61M25/0141 ,  A61M25/0158

Abstract: A elongate tubular catheter uses spirally sliced tubes to provide flexible support having pushability in a number of roles. The spirally sliced tube may be used in place of a stiffening tube thereby providing a catheter that can have variable degrees of flexibility along its length. Alternatively, the spirally sliced tube may be used in place of a compression wire or other puller wire sleeve. The spirally sliced tubes may also be used as the inner or outer wall of an irrigation lumen within the catheter. The flexibility of the catheter can be easily modified during manufacture by varying the pitch angle of the spiral slice. Flexibility along the length of the catheter can also be modified by using one or more spirally sliced tubes or tubes in which only portions are spirally sliced.

Abstract translation: 细长的管状导管使用螺旋切片管来提供具有多种作用的可推动性的柔性支撑。 可以使用螺旋切片的管代替加强管，从而提供可沿其长度具有不同程度的柔性的导管。 或者，可以使用螺旋切片的管代替压缩丝或其它拉丝套筒。 螺旋切片的管也可以用作导管内的冲洗腔的内壁或外壁。 通过改变螺旋切片的俯仰角，可以在制造过程中容易地改变导管的柔性。 沿着导管长度的灵活性也可以通过使用一个或多个螺旋切片的管或管进行修改，其中只有部分被螺旋切片。

公开(公告)号：US06669621B2

公开(公告)日：2003-12-30

申请号：US09805961

申请日：2001-03-14

Applicant: Michael Dennis O'Hara ,  Benjamin David McDaniel

Inventor： Michael Dennis O'Hara ,  Benjamin David McDaniel

IPC: A61M3600

CPC classification number: A61N5/1002 ,  A61N2005/1025

Abstract: A radioactive substance absorber is incorporated into an intravascular radiotherapy source ribbon assembly to prevent the migration of radioactive matter throughout the assembly container. The radioactive substance absorber comprises carbon in various forms and configurations. The radioactive substance absorber is positioned in proximity to the source core and absorbs radioactive materials which break free from the source core, thereby containing the radioactive material.

Abstract translation: 将放射性物质吸收剂并入血管内放射治疗源带组件中，以防止放射性物质在组装容器内的迁移。 放射性物质吸收剂包括各种形式和构型的碳。 放射性物质吸收器位于源芯附近，并吸收从源芯脱离的放射性物质，从而含有放射性物质。