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公开(公告)号:US20050107288A1
公开(公告)日:2005-05-19
申请号:US10490192
申请日:2002-09-06
申请人: Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
发明人: Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
摘要: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
摘要翻译: 本发明涉及通式(I)的化合物,其制备方法,包含它们的药物组合物及其在治疗人或动物疾病中的用途。
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公开(公告)号:US07405201B2
公开(公告)日:2008-07-29
申请号:US10490192
申请日:2002-09-06
申请人: Berthold Hinzen , Heike Brötz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
发明人: Berthold Hinzen , Heike Brötz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
摘要: The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
摘要翻译: 本发明涉及通式(I)的化合物,其制备方法,包含它们的药物组合物及其在治疗人或动物疾病中的用途。
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公开(公告)号:US06548538B2
公开(公告)日:2003-04-15
申请号:US09973753
申请日:2001-10-09
申请人: Klaus Urbahns , Michael Woltering , Susanne Nikolic , Josef Pernerstorfer , Berthold Hinzen , Elke Dittrich-Wengenroth , Hilmar Bischoff , Claudia Hirth-Dietrich , Klemens Lustig
发明人: Klaus Urbahns , Michael Woltering , Susanne Nikolic , Josef Pernerstorfer , Berthold Hinzen , Elke Dittrich-Wengenroth , Hilmar Bischoff , Claudia Hirth-Dietrich , Klemens Lustig
IPC分类号: A61K31341
CPC分类号: C07D307/52 , C07C229/18 , C07C229/34 , C07C237/04 , C07C317/28 , C07C323/52 , C07C2601/14 , C07D263/32 , C07D333/20
摘要: The present application relates to novel potent PPAR-alpha-activating compounds for treating, for example, coronary heart disease, and to their preparation.
摘要翻译: 本申请涉及用于治疗例如冠心病的新型有效的PPAR-α活化化合物及其制备。
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公开(公告)号:US06750236B2
公开(公告)日:2004-06-15
申请号:US10349448
申请日:2003-01-22
申请人: Klaus Urbahns , Michael Woltering , Susanne Nikolic , Josef Pernerstorfer , Berthold Hinzen , Elke Dittrich-Wengenroth , Hilmar Bischoff , Claudia Hirth-Dietrich , Klemens Lustig
发明人: Klaus Urbahns , Michael Woltering , Susanne Nikolic , Josef Pernerstorfer , Berthold Hinzen , Elke Dittrich-Wengenroth , Hilmar Bischoff , Claudia Hirth-Dietrich , Klemens Lustig
IPC分类号: A61K31421
CPC分类号: C07D307/52 , C07C229/18 , C07C229/34 , C07C237/04 , C07C317/28 , C07C323/52 , C07C2601/14 , C07D263/32 , C07D333/20
摘要: This invention relates to novel potent PPAR-alpha-activating compounds which are useful in the treatment of diseases such as coronary heart disease. The invention also relates to methods of preparation of PPAR-alpha-activating compounds.
摘要翻译: 本发明涉及可用于治疗诸如冠心病的疾病的新型有效的PPAR-α活化化合物。 本发明还涉及制备PPAR-α活化化合物的方法。
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