公开(公告)号：US20240258569A1

公开(公告)日：2024-08-01

申请号：US18627460

申请日：2024-04-05

Applicant: SOULBRAIN CO., LTD.

Inventor： Min Goo KIM ,  Min Jung JANG ,  Jae Yoon KIM ,  Sang Ho LEE ,  Jong Cheol YUN ,  Ji Seong HAN

IPC: H01M10/0567 ,  C01B17/45 ,  C07C317/28 ,  H01M10/0525

CPC classification number: H01M10/0567 ,  C01B17/45 ,  C07C317/28 ,  H01M10/0525 ,  C01P2006/40 ,  H01M2300/0025

Abstract: Disclosed is an electrolyte and a secondary battery containing the same. According to the present disclosure, charging efficiency and output may be improved due to low discharge resistance, and gas generation and thickness increase may be suppressed to provide a secondary battery with long-term lifespan and excellent high temperature capacity retention.

公开(公告)号：US20240254075A1

公开(公告)日：2024-08-01

申请号：US18558726

申请日：2022-05-06

Applicant: Autobahn Therapeutics, Inc.

Inventor： Brian Andrew STEARNS ,  Jill Melissa BACCEI ,  Jason Randall HARRIS

IPC: C07C235/20 ,  A61K31/16 ,  A61K31/165 ,  A61K31/397 ,  A61K31/40 ,  A61K31/42 ,  A61K31/44 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/455 ,  A61K31/4965 ,  A61K31/50 ,  A61K31/505 ,  A61K31/5375 ,  A61P25/00 ,  C07C235/16 ,  C07C235/22 ,  C07C235/24 ,  C07C243/28 ,  C07C255/29 ,  C07C259/06 ,  C07C313/02 ,  C07C317/28 ,  C07D205/04 ,  C07D213/75 ,  C07D237/20 ,  C07D237/22 ,  C07D239/42 ,  C07D241/20 ,  C07D261/14 ,  C07D295/18 ,  C07D305/08

CPC classification number: C07C235/20 ,  A61K31/16 ,  A61K31/165 ,  A61K31/397 ,  A61K31/40 ,  A61K31/42 ,  A61K31/44 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/455 ,  A61K31/4965 ,  A61K31/50 ,  A61K31/505 ,  A61K31/5375 ,  A61P25/00 ,  C07C235/16 ,  C07C235/22 ,  C07C235/24 ,  C07C243/28 ,  C07C255/29 ,  C07C259/06 ,  C07C313/02 ,  C07C317/28 ,  C07D205/04 ,  C07D213/75 ,  C07D237/20 ,  C07D237/22 ,  C07D239/42 ,  C07D241/20 ,  C07D261/14 ,  C07D295/18 ,  C07D305/08 ,  C07C2601/02 ,  C07C2601/14

Abstract: Provided herein are fatty acid amide (FAAH) cleavable prodrugs of thyromimetics and pharmaceutical compositions comprising these compounds with at least one pharmaceutically acceptable excipient further comprising a peripherally restricted FAAH inhibitor.

公开(公告)号：US20230180761A1

公开(公告)日：2023-06-15

申请号：US18166601

申请日：2023-02-09

Applicant: CORTEVA AGRISCIENCE LLC

Inventor： RONALD J. HEEMSTRA ,  RONALD ROSS, JR. ,  KYLE A. DEKORVER ,  KAITLYN GRAY ,  DANIEL I. KNUEPPEL ,  PETER VEDNOR ,  TIMOTHY P. MARTIN ,  JOSEPH D. ECKELBARGER ,  JOHN F. DAEUBLE, SR. ,  RICKY HUNTER ,  DAVID A. DEMETER ,  TONY K. TRULLINGER ,  ERICH W. BAUM ,  ZOLTAN L. BENKO ,  NAKYEN CHOY ,  GARY D. CROUSE ,  FANGZHENG LI ,  JEFFREY NISSEN ,  MONICA B. OLSON ,  MICHELLE RIENER ,  THOMAS C. SPARKS ,  FRANK J. WESSELS ,  MAURICE C. YAP

IPC: A01N53/00 ,  C07C255/46 ,  C07C255/57 ,  C07C255/60 ,  C07C259/10 ,  C07D213/84 ,  C07D213/89 ,  C07D215/227 ,  C07C271/28 ,  C07C271/66 ,  C07D215/38 ,  C07D231/56 ,  C07D233/36 ,  C07C311/08 ,  C07C311/46 ,  C07D235/30 ,  C07C317/28 ,  C07C317/40 ,  C07C317/50 ,  C07C323/41 ,  C07C323/42 ,  C07C323/59 ,  C07C331/12 ,  C07C381/10 ,  C07D205/04 ,  C07C237/42 ,  C07D207/452 ,  C07C255/29 ,  C07D209/49 ,  C07D213/75 ,  C07D213/81 ,  C07D309/14 ,  C07D231/12 ,  C07D331/04 ,  C07D333/36 ,  C07D249/08 ,  C07D207/10 ,  C07D285/06 ,  C07D295/32 ,  C07D305/08 ,  C07D207/273 ,  C07D233/80 ,  C07D261/12 ,  C07D263/26 ,  C07D277/36 ,  C07D307/33 ,  C07D333/48 ,  C07C237/22 ,  C07D213/56 ,  C07D277/30 ,  C07D307/52 ,  C07D333/60 ,  A01N37/22 ,  A01N37/34 ,  A01N41/10 ,  A01N43/40 ,  A01N43/60 ,  A01N43/653 ,  A01N43/707 ,  A01N43/82 ,  A01N43/90 ,  C07C233/63 ,  C07C233/65 ,  C07C317/14 ,  C07D241/20 ,  C07D253/07 ,  C07D487/04

CPC classification number: A01N53/00 ,  C07C255/46 ,  C07C255/57 ,  C07C255/60 ,  C07C259/10 ,  C07D213/84 ,  C07D213/89 ,  C07D215/227 ,  C07C271/28 ,  C07C271/66 ,  C07D215/38 ,  C07D231/56 ,  C07D233/36 ,  C07C311/08 ,  C07C311/46 ,  C07D235/30 ,  C07C317/28 ,  C07C317/40 ,  C07C317/50 ,  C07C323/41 ,  C07C323/42 ,  C07C323/59 ,  C07C331/12 ,  C07C381/10 ,  C07D205/04 ,  C07C237/42 ,  C07D207/452 ,  C07C255/29 ,  C07D209/49 ,  C07D213/75 ,  C07D213/81 ,  C07D309/14 ,  C07D231/12 ,  C07D331/04 ,  C07D333/36 ,  C07D249/08 ,  C07D207/10 ,  C07D285/06 ,  C07D295/32 ,  C07D305/08 ,  C07D207/273 ,  C07D233/80 ,  C07D261/12 ,  C07D263/26 ,  C07D277/36 ,  C07D307/33 ,  C07D333/48 ,  C07C237/22 ,  C07D213/56 ,  C07D277/30 ,  C07D307/52 ,  C07D333/60 ,  A01N37/22 ,  A01N37/34 ,  A01N41/10 ,  A01N43/40 ,  A01N43/60 ,  A01N43/653 ,  A01N43/707 ,  A01N43/82 ,  A01N43/90 ,  C07C233/63 ,  C07C233/65 ,  C07C317/14 ,  C07D241/20 ,  C07D253/07 ,  C07D487/04 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14

Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).

公开(公告)号：US10080735B2

公开(公告)日：2018-09-25

申请号：US15712269

申请日：2017-09-22

Applicant: OLATEC THERAPEUTICS LLC

Inventor： Joseph St. Laurent

IPC: A01N37/34 ,  A61K31/275 ,  A61K9/00 ,  A61K9/06 ,  A61K47/10 ,  C07C317/28

CPC classification number: A61K31/275 ,  A61K9/0014 ,  A61K9/0053 ,  A61K9/06 ,  A61K47/10 ,  C07C317/28

Abstract: The present invention relates to purified 3-methanesulfonylpropionitrile or a pharmaceutically acceptable salt thereof, and a method for preparing such compound. The compound has at least 90% (w/w) purity. The present invention is also directed to a pharmaceutical composition comprises the purified compound and a pharmaceutically acceptable carrier. The present invention is further directed to a method for treating inflammation, inflammatory-related disorders, or pain, by administering 3-methanesulfonylpropionitrile or a pharmaceutically acceptable salt or solvate thereof to a subject in need thereof.

公开(公告)号：US20180230097A1

公开(公告)日：2018-08-16

申请号：US15577102

申请日：2016-05-26

Applicant: LUPIN LIMITED

Inventor： Palash SANPHUI ,  Ananda Pundlik SAPDHARE ,  Arunkumar Digambar PATIL ,  Hemraj Mahadeorao LANDE ,  Gurvinder Pal SINGH ,  Purna Chandra RAY ,  Nandu Bahan BHISE ,  Girij Pal SINGH ,  Mithun Dasharath SURWASE ,  Shantanu Gokuldas VARADE ,  Govind Dnyanoba AUSEKAR ,  Radhakrishna Bhikaji SHIVDAVKAR

IPC: C07D209/48

CPC classification number: C07D209/48 ,  C07B2200/07 ,  C07C315/04 ,  C07C317/28

Abstract: The present invention provides an improved process for preparation of an intermediate of apremilast. The present invention also provides an improved process for preparation of apremilast. This invention also provides novel polymorphs of apremilast. The present invention also provides pharmaceutical compositions of novel polymorphs of apremilast. This invention also provides a process for preparation of novel polymorphs of apremilast, which are cost-effective, robust, and viable at plant scale.

公开(公告)号：US20180180992A1

公开(公告)日：2018-06-28

申请号：US15854244

申请日：2017-12-26

Applicant: Shin-Etsu Chemical Co., Ltd.

Inventor： Masaaki Kotake ,  Keiichi Masunaga ,  Satoshi Watanabe ,  Masaki Ohashi

IPC: G03F7/004 ,  C07C381/12

CPC classification number: G03F7/004 ,  C07C317/04 ,  C07C317/28 ,  C07C381/12 ,  G03F7/0045 ,  G03F7/033 ,  G03F7/0392 ,  G03F7/0395 ,  G03F7/0397 ,  G03F7/2059 ,  G03F7/322

Abstract: A positive resist composition comprising a polymer adapted to be decomposed under the action of acid to increase its solubility in alkaline developer and a sulfonium compound of formula (A) has a high resolution. When the resist composition is processed by lithography, a pattern with minimal LER can be formed.

公开(公告)号：US10003102B2

公开(公告)日：2018-06-19

申请号：US14705819

申请日：2015-05-06

Applicant: SAMSUNG SDI CO., LTD.

Inventor： Erang Cho ,  Duckhyun Kim ,  Moonsung Kim ,  Jeonghye Lee ,  Woocheol Shin

IPC: H01M10/0567 ,  H01M6/16 ,  C07C317/28 ,  C07D333/24 ,  C07D213/57 ,  H01M10/052

CPC classification number: H01M10/0567 ,  C07C317/28 ,  C07C2601/08 ,  C07D213/57 ,  C07D333/24 ,  H01M6/168 ,  H01M10/052 ,  H01M2300/0025

Abstract: An electrolyte additive for a lithium battery, an electrolyte including the electrolyte additive, and a lithium battery including the electrolyte additive are disclosed. The electrolyte additive for a lithium battery includes a sulfonylmethylisocyanide-based compound. The electrolyte additive including the sulfonylmethylisocyanide-based compound may form a protective layer having improved high-temperature stability on positive and negative electrodes of a lithium battery, thereby improving the safety of the lithium battery.

公开(公告)号：US20180030063A1

公开(公告)日：2018-02-01

申请号：US15683189

申请日：2017-08-22

Applicant: Alkermes Pharma Ireland Limited

Inventor： Tarek A. Zeidan ,  Scott Duncan ,  Christopher P. Hencken ,  Thomas Andrew Wynn ,  Carlos N. Sanrame

IPC: C07D491/113 ,  C07C229/18 ,  C07C317/18 ,  C07C317/28 ,  C07D207/408 ,  C07D211/92 ,  C07D295/088 ,  C07C229/12 ,  C07D207/12 ,  C07D207/40 ,  A61K31/4015

CPC classification number: C07D491/113 ,  A61K31/4015 ,  C07C229/12 ,  C07C229/18 ,  C07C317/18 ,  C07C317/28 ,  C07D207/12 ,  C07D207/40 ,  C07D207/408 ,  C07D211/92 ,  C07D295/088

Abstract: The present invention provides compounds of formula (I), wherein: R1 is unsubstituted C1-C6 alkyl; La is substituted or unsubstituted C1-C6 alkyl linker, substituted or unsubstituted C3-C10 carbocycle, substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S, or substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S; and R2 and R3 are each, independently, H, substituted or unsubstituted C1-C6 alkyl, or substituted or unsubstituted C6-C10 aryl; or alternatively, R2 and R3, together with the nitrogen atom to which they are attached, form a substituted or unsubstituted heteroaryl comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S or a substituted or unsubstituted heterocycle comprising one or two 5- or 6-member rings and 1-4 heteroatoms selected from N, O and S. The invention also provides pharmaceutical compositions and methods for treating neurological diseases, such as multiple sclerosis.

公开(公告)号：US20170369426A1

公开(公告)日：2017-12-28

申请号：US15615276

申请日：2017-06-06

Applicant: Achaogen, Inc.

Inventor： Brian D. Patterson ,  Qing Lu ,  James Bradley Aggen ,  Paola Dozzo ,  Ramesh Annasaheb Kasar ,  Martin Sheringham Linsell ,  Timothy Robert Kane ,  Micah James Gliedt ,  Darin James Hildebrandt ,  Glenn A. McEnroe ,  Frederick Cohen

IPC: C07C259/06 ,  C07D333/70 ,  C07C313/04 ,  C07C313/12 ,  C07D213/81 ,  C07D213/79 ,  C07D213/64 ,  C07C323/60 ,  C07C323/42 ,  C07C317/50 ,  C07C317/46 ,  C07C317/28 ,  C07D471/04 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08

CPC classification number: C07C259/06 ,  C07C313/04 ,  C07C313/12 ,  C07C317/28 ,  C07C317/46 ,  C07C317/50 ,  C07C323/42 ,  C07C323/60 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07D213/64 ,  C07D213/79 ,  C07D213/81 ,  C07D333/70 ,  C07D471/04

Abstract: Antibacterial compounds of formula (I) are provided: as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

公开(公告)号：US09795140B2

公开(公告)日：2017-10-24

申请号：US15092646

申请日：2016-04-07

Applicant: Dow AgroSciences LLC

Inventor： Timothy P. Martin ,  Joseph D. Eckelbarger ,  Ronald Ross, Jr. ,  Kyle DeKorver ,  Ronald J. Heemstra ,  Daniel I. Knueppel ,  Peter Vednor ,  Ricky Hunter ,  David A. Demeter ,  Tony K. Trullinger ,  Erich Baum ,  Zoltan Benko ,  Nakyen Choy ,  Gary Crouse ,  John F. Daeuble, Sr. ,  Fangzheng Li ,  Jeff Nissen ,  Michelle Riener ,  Tom Sparks ,  Frank Wessels ,  Maurice Yap

IPC: A01N53/00 ,  A01N43/90 ,  C07D207/273 ,  A01N43/82 ,  C07D307/33 ,  C07D277/36 ,  C07D263/26 ,  C07D261/12 ,  C07D333/48 ,  C07D307/52 ,  C07D277/30 ,  C07D213/56 ,  C07C237/22 ,  C07D333/60 ,  C07D233/80 ,  C07D487/04 ,  A01N43/707 ,  A01N43/653 ,  A01N43/60 ,  A01N43/40 ,  A01N41/10 ,  A01N37/34 ,  A01N37/22 ,  C07D253/07 ,  C07D241/20 ,  C07C317/14 ,  C07C233/65 ,  C07C233/63 ,  C07D209/49 ,  C07C381/10 ,  C07D205/04 ,  C07C237/42 ,  C07D207/10 ,  C07D207/452 ,  C07C255/29 ,  C07C255/57 ,  C07D285/06 ,  C07D295/32 ,  C07D305/08 ,  C07C255/46 ,  C07D213/75 ,  C07C255/60 ,  C07C259/10 ,  C07D213/81 ,  C07D213/84 ,  C07D309/14 ,  C07D213/89 ,  C07D215/227 ,  C07C271/28 ,  C07C271/66 ,  C07D231/12 ,  C07D331/04 ,  C07D231/56 ,  C07D333/36 ,  C07D233/36 ,  C07C311/08 ,  C07C311/46 ,  C07D235/30 ,  C07C317/28 ,  C07C317/40 ,  C07C317/50 ,  C07C323/41 ,  C07C323/42 ,  C07C323/59 ,  C07D249/08 ,  C07C331/12 ,  C07D215/38

CPC classification number: A01N53/00 ,  A01N37/22 ,  A01N37/34 ,  A01N41/10 ,  A01N43/40 ,  A01N43/60 ,  A01N43/653 ,  A01N43/707 ,  A01N43/82 ,  A01N43/90 ,  C07C233/63 ,  C07C233/65 ,  C07C237/22 ,  C07C237/42 ,  C07C255/29 ,  C07C255/46 ,  C07C255/57 ,  C07C255/60 ,  C07C259/10 ,  C07C271/28 ,  C07C271/66 ,  C07C311/08 ,  C07C311/46 ,  C07C317/14 ,  C07C317/28 ,  C07C317/40 ,  C07C317/50 ,  C07C323/41 ,  C07C323/42 ,  C07C323/59 ,  C07C331/12 ,  C07C381/10 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/14 ,  C07D205/04 ,  C07D207/10 ,  C07D207/273 ,  C07D207/452 ,  C07D209/49 ,  C07D213/56 ,  C07D213/75 ,  C07D213/81 ,  C07D213/84 ,  C07D213/89 ,  C07D215/227 ,  C07D215/38 ,  C07D231/12 ,  C07D231/56 ,  C07D233/36 ,  C07D233/80 ,  C07D235/30 ,  C07D241/20 ,  C07D249/08 ,  C07D253/07 ,  C07D261/12 ,  C07D263/26 ,  C07D277/30 ,  C07D277/36 ,  C07D285/06 ,  C07D295/32 ,  C07D305/08 ,  C07D307/33 ,  C07D307/52 ,  C07D309/14 ,  C07D331/04 ,  C07D333/36 ,  C07D333/48 ,  C07D333/60 ,  C07D487/04

Abstract: This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”).