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公开(公告)号:US20130130930A1
公开(公告)日:2013-05-23
申请号:US13681274
申请日:2012-11-19
申请人: Bhairavi PARIKH , Michael D. BRODY , James STONE , Brian AWABDY , Urvi VED , Anh TRAN , Patrick J. COLLINS , David J. ANVAR
发明人: Bhairavi PARIKH , Michael D. BRODY , James STONE , Brian AWABDY , Urvi VED , Anh TRAN , Patrick J. COLLINS , David J. ANVAR
IPC分类号: C12Q1/68
CPC分类号: G01N33/5005 , C12Q1/68 , C12Q1/6806 , C12Q1/686 , C12Q1/6883 , G01N33/689
摘要: A method for concentrating and isolating nucleated cells, such as maternal and fetal nucleated red blood cells (nRBCs), in a maternal whole blood sample. The invention also provides methods and apparatus for preparing to analyze and analyzing the sample for identification of fetal genetic material as part of prenatal genetic testing. The invention also pertains to methods and apparatus for discriminating fetal nucleated red blood cells from maternal nucleated red blood cells obtained from a blood sample taken from a pregnant woman.