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公开(公告)号：US20230364614A1
公开(公告)日：2023-11-16
申请号：US18227212
申请日：2023-07-27
发明人： Iago Pereiro Pereiro , Anna Fomitcheva Khartchenko , Robert Dean Lovchik , Govind Kaigala , Lorenzo Franco Teodoro Petrini , Anel Zulji , Frédéric M. Buffière , Johann Guégan , Eliane Rivalin , Sylvie Villard-Saussine
IPC分类号： B01L3/00
CPC分类号： B01L3/502784 , B01L3/502746 , B01L2200/027 , B01L2300/0832 , B01L2400/0487 , B01L2400/0622
摘要： In one implementation, a microfluidic probe has a non-planar processing surface and an inlet aperture. The shape of the surface may be selected to produce a specific velocity gradient profile across a surface onto which fluid is deposited using the microfluidic probe, for example a constant velocity gradient or a velocity gradient that decreases linearly with distance from the inlet aperture. The microfluidic probe may define and overflow notch in a perimeter edge of the processing surface.
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公开(公告)号：US10732189B2
公开(公告)日：2020-08-04
申请号：US15543579
申请日：2016-01-14
申请人： BIO-RAD LABORATORIES, INC. , BIO-RAD INNOVATIONS , Frederic Buffiere , Sylvie Villard-Saussine , Eliane Rivalin , Laurent Guillon , Johann Guegan
IPC分类号： G01N33/80 , B01L3/00 , G01N33/543
摘要： Blood typing systems and methods are provided. In one embodiment, the method may be achieved by applying a sample to a surface of a substrate having one or more binding agents immobilized thereon, wherein the one or more binding agents are capable of binding to one or more substances in the sample; substantially removing unbound material from at least a portion of the substrate having immobilized binding agent; and detecting substances bound to the one or more binding agents immobilized on the substrate; wherein the applying the sample to the surface of the substrate step is concurrent with the removing unbound material from at least a portion of the substrate step. Systems and other methods are also described and illustrated.
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