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公开(公告)号：US20160074406A1
公开(公告)日：2016-03-17
申请号：US14947482
申请日：2015-11-20
发明人： Tianwei Chou , Augustus O. Okhamafe
IPC分类号： A61K31/519 , A61J1/14 , A61K9/48 , A61K9/00 , A61K31/405
CPC分类号： A61K31/519 , A61J1/1418 , A61K9/0053 , A61K9/009 , A61K9/145 , A61K9/4816 , A61K9/4825 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K31/405
摘要： Dry blend powder formulations comprising a pharmaceutical formulation containing tetrahydrobiopterin, and methods of making and using the same, are disclosed herein.
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公开(公告)号：US11911446B2
公开(公告)日：2024-02-27
申请号：US16837905
申请日：2020-04-01
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O. Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
IPC分类号： A61K38/22 , A61K38/17 , A61K9/19 , A61K47/12 , A61K47/26 , A61K47/10 , A61K9/00 , A61K47/20 , A61K47/18
CPC分类号： A61K38/2242 , A61K9/0019 , A61K9/19 , A61K38/1709 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/26
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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公开(公告)号：US20240156914A1
公开(公告)日：2024-05-16
申请号：US18425954
申请日：2024-01-29
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O. Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
IPC分类号： A61K38/22 , A61K9/00 , A61K9/19 , A61K38/17 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/20 , A61K47/26
CPC分类号： A61K38/2242 , A61K9/0019 , A61K9/19 , A61K38/1709 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/26
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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公开(公告)号：US10646550B2
公开(公告)日：2020-05-12
申请号：US15880002
申请日：2018-01-25
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O. Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
IPC分类号： A61K38/22 , A61K38/00 , A61K38/16 , A61K9/19 , A61K47/12 , A61K47/26 , A61K47/18 , A61K47/10 , A61K9/00 , A61K38/17
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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公开(公告)号：US20130108694A1
公开(公告)日：2013-05-02
申请号：US13666697
申请日：2012-11-01
发明人： Tianwei Chou , Augustus O. Okhamafe
IPC分类号： A61K31/519 , A61P7/06 , A61P3/02 , A61P25/00 , A61P9/00 , B65D41/04 , A61P29/00 , A61P5/50 , A61P13/12 , A61P9/12 , A61J1/03 , A61K9/48 , A61P9/10
CPC分类号： A61K31/519 , A61J1/1418 , A61K9/0053 , A61K9/009 , A61K9/145 , A61K9/4816 , A61K9/4825 , A61K9/485 , A61K9/4858 , A61K9/4866 , A61K31/405
摘要： Dry blend powder formulations comprising a pharmaceutical formulation containing tetrahydrobiopterin, and methods of making and using the same, are disclosed herein.
摘要翻译： 本文公开了包含含有四氢生物蝶呤的药物制剂的干混粉末制剂及其制备及使用方法。
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公开(公告)号：US12076372B2
公开(公告)日：2024-09-03
申请号：US18157573
申请日：2023-01-20
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O. Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
IPC分类号： A61K38/22 , A61K9/00 , A61K9/19 , A61K38/00 , A61K38/16 , A61K38/17 , A61K47/10 , A61K47/12 , A61K47/18 , A61K47/20 , A61K47/26
CPC分类号： A61K38/2242 , A61K9/0019 , A61K9/19 , A61K38/1709 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/26
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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公开(公告)号：US20200246433A1
公开(公告)日：2020-08-06
申请号：US16837905
申请日：2020-04-01
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O. Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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公开(公告)号：US09907834B2
公开(公告)日：2018-03-06
申请号：US15225355
申请日：2016-08-01
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O. Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
IPC分类号： A61K38/00 , A61K38/22 , A61K9/19 , A61K47/12 , A61K47/26 , A61K47/18 , A61K47/10 , A61K9/00 , A61K38/17
CPC分类号： A61K38/2242 , A61K9/0019 , A61K9/19 , A61K38/1709 , A61K47/10 , A61K47/12 , A61K47/183 , A61K47/26
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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公开(公告)号：US11590204B2
公开(公告)日：2023-02-28
申请号：US16837910
申请日：2020-04-01
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O. Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
IPC分类号： A61K38/22 , A61K38/00 , A61K38/16 , A61K9/19 , A61K47/12 , A61K47/26 , A61K47/10 , A61K9/00 , A61K38/17 , A61K47/20 , A61K47/18
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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公开(公告)号：US20200246434A1
公开(公告)日：2020-08-06
申请号：US16837910
申请日：2020-04-01
发明人： Sherry Bullens , Stuart Bunting , Tianwei Chou , Augustus O Okhamafe , Christopher P. Price , Daniel J. Wendt , Clarence Yap
摘要： The present disclosure provides for use of variants of C-type natriuretic peptide (CNP), and novel pharmaceutical compositions and formulations comprising CNP variant peptides for the treatment of skeletal dysplasias, one or more symptoms of skeletal dysplasias, such as long bone growth or growth velocity, and other disorders having a skeletal dysplasia and/or CNP-associated symptom or component.
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