公开(公告)号：US20220089704A1

公开(公告)日：2022-03-24

申请号：US17288445

申请日：2019-10-28

Applicant: Biogen MA Inc. ,  National Research Council of Canada

Inventor： Benjamin A. Smith ,  Andreas Lehmann ,  Thomas O. Cameron ,  R. Blake Pepinsky ,  Dingyi Wen ,  Graham K. Farrington ,  Gopalan Raghunathan ,  Nels E. Pederson ,  Danica Stanimirovic ,  Traian Sulea ,  Arsalan S. Haqqani

IPC: C07K16/18 ,  A61P25/28 ,  C07K16/28 ,  C07K14/47

Abstract: Featured are compositions comprising humanized and engineered variants of an antibody variable domain (e.g., FC5), chimeric molecules comprising same, compositions comprising same, and uses thereof.

公开(公告)号：US11827702B2

公开(公告)日：2023-11-28

申请号：US17900161

申请日：2022-08-31

Applicant: Biogen MA Inc.

Inventor： Isin Dalkilic-Liddle ,  Benjamin A. Smith ,  Karl J. M. Hanf ,  Fang Qian ,  R. Blake Pepinsky ,  Thomas O. Cameron

IPC: C07K16/28 ,  C12N15/113

CPC classification number: C07K16/28 ,  C12N15/113 ,  C07K2317/565

Abstract: The present disclosure provides anti-transferrin receptor antibodies, compositions comprising the same and methods of their use. This disclosure also provides polynucleotides and vectors encoding the anti-transferrin receptor antibodies and cells comprising the same, methods of making the antibodies, and molecules comprising the antibodies.

公开(公告)号：US20240158494A1

公开(公告)日：2024-05-16

申请号：US18490319

申请日：2023-10-19

Applicant: Biogen MA Inc.

Inventor： Isin Dalkilic-Liddle ,  Benjamin A. Smith ,  Karl J.M. Hanf ,  Fang Qian ,  R. Blake Pepinsky ,  Thomas O. Cameron

IPC: C07K16/28 ,  C12N15/113

CPC classification number: C07K16/28 ,  C12N15/113 ,  C07K2317/565

Abstract: The present disclosure provides anti-transferrin receptor antibodies, compositions comprising the same and methods of their use. This disclosure also provides polynucleotides and vectors encoding the anti-transferrin receptor antibodies and cells comprising the same, methods of making the antibodies, and molecules comprising the antibodies.

公开(公告)号：US20230131379A1

公开(公告)日：2023-04-27

申请号：US17900161

申请日：2022-08-31

Applicant: Biogen MA Inc.

Inventor： Isin Dalkilic-Liddle ,  Benjamin A. Smith ,  Karl J. M. Hanf ,  Fang Qian ,  R. Blake Pepinsky ,  Thomas O. Cameron

IPC: C07K16/28 ,  C12N15/113

Abstract: The present disclosure provides anti-transferrin receptor antibodies, compositions comprising the same and methods of their use. This disclosure also provides polynucleotides and vectors encoding the anti-transferrin receptor antibodies and cells comprising the same, methods of making the antibodies, and molecules comprising the antibodies.