公开(公告)号：US20250018642A1

公开(公告)日：2025-01-16

申请号：US18899826

申请日：2024-09-27

Applicant: XEROX CORPORATION ,  NATIONAL RESEARCH COUNCIL OF CANADA

Inventor： Sarah J. VELLA ,  Alexandros VASILEIOU ,  Yujie ZHU ,  Edward G. ZWARTZ ,  Chantal PAQUET ,  Silvio E. KRUGER ,  Mohammad RAFIEE ,  Yujie ZHANG ,  Thomas LACELLE ,  Derek ARANGUREN VAN EGMOND ,  Claudie ROY

IPC: B29C64/118 ,  B29C48/05 ,  B29C64/10 ,  B29C64/165 ,  B29C64/314 ,  B29C64/40 ,  B29K25/00 ,  B29K33/00 ,  B29K67/00 ,  B29K101/12 ,  B29K105/00 ,  B29K105/04 ,  B29K105/16 ,  B29K507/04 ,  B29K509/00 ,  B29K509/02 ,  B33Y10/00 ,  B33Y40/10 ,  B33Y70/10 ,  B33Y80/00 ,  C08K3/04 ,  C08K3/22 ,  C08K7/06 ,  C08K9/04 ,  C08L23/06 ,  C08L25/06 ,  C08L53/02 ,  C08L67/04 ,  C08L71/02 ,  C09D4/06 ,  C09D5/24 ,  C09D7/40 ,  C09D7/61 ,  C09D7/62 ,  C09D7/63 ,  C09D167/04 ,  H10N30/092 ,  H10N30/85

Abstract: Parts made by additive manufacturing are often structural in nature, rather than having functional properties conveyed by a polymer or other component present therein. Printed parts having piezoelectric properties may be formed using compositions comprising a plurality of piezoelectric particles dispersed in at least a portion of a polymer matrix comprising first polymer material and a sacrificial material, the sacrificial material being removable from the polymer matrix to define a plurality of pores in the polymer matrix. The piezoelectric particles may remain substantially non-agglomerated when combined with the polymer matrix. The sacrificial material may comprise a second polymer material. The compositions may define a composite having a form factor such as a composite filament, a composite pellet, a composite powder, or a composite paste. Additive manufacturing processes may comprise forming a printed part by depositing the compositions layer-by-layer and introducing porosity therein.

公开(公告)号：US12181431B2

公开(公告)日：2024-12-31

申请号：US17267184

申请日：2019-08-13

Applicant: National Research Council of Canada

Inventor： Chang Guo ,  Jianying Ouyang ,  Zhao Li ,  Jianfu Ding ,  Patrick Roland Lucien Malenfant

IPC: G01N27/12 ,  B82Y30/00 ,  B82Y40/00 ,  C01B32/172 ,  C01B32/174 ,  C08G61/12 ,  B82Y35/00

Abstract: A compound of Formula (0): where Ar is one or more substituted or unsubstituted aromatic units, R is independently H, F, CN, a C1-C20 linear or branched aliphatic group or a C1-C20 linear or branched aliphatic acyl group, and n is an integer 3 or greater, is useful for sorting and dispersing carbon nanotubes (CNTs) and for producing printed electronic devices (e.g. CO2 sensors, TFTs) in which the CNTs are functionalized with the compound.

公开(公告)号：US20240425875A1

公开(公告)日：2024-12-26

申请号：US18691190

申请日：2022-09-12

Applicant: National Research Council of Canada

Inventor： Yves DUROCHER ,  Simon JOUBERT ,  Sylvie PERRET ,  Martin LOIGNON ,  Jean-Sebastien MALTAIS ,  Simon LORD-DUFOUR

IPC: C12N15/85 ,  C07K14/21 ,  C12P21/02

Abstract: Provided are methods, expression systems, kits, and vectors for constitutive and/or cumate-inducible expression of a gene of interest in CHO cells. The expression systems and methods described herein employ CHO cells that are stably transfected with a nucleic acid molecule encoding a reverse cumate transactivator (rcTA), the expression of which is regulated by a cymene repressor (CymR). for constitutive and/or cumate-inducible expression of a gene of interest.

公开(公告)号：US12174218B2

公开(公告)日：2024-12-24

申请号：US17638937

申请日：2020-08-31

Applicant: National Research Council of Canada ,  The Governors of the University of Alberta

Inventor： Robert A. Wolkow ,  Jason Pitters ,  Mark Salomons

IPC: G01Q10/02 ,  G01Q10/04 ,  H02N2/02

Abstract: A nano-positioning system for fine and coarse nano-positioning including at least one actuator, wherein the at least one actuator includes a high Curie temperature material and wherein the nano-positioning system is configured to apply a voltage to the at least one actuator to generate fine and/or coarse motion by the at least one actuator. The nano-positioning system being a stand-alone system, a scanning probe microscope, or an attachment to an existing microscope configured to perform a method of creepless nano-positioning that includes positioning a probe relative to a first area of a substrate using coarse stepping and interacting with the first area of the substrate using fine motion after less than 60 seconds of the positioning the probe. The movement of the scanning probe microscope is actuated by a high Curie temperature piezoelectric material that limits and/or eliminates creep, hysteresis and aging.

公开(公告)号：US12153988B2

公开(公告)日：2024-11-26

申请号：US17786839

申请日：2020-12-18

Applicant: NATIONAL RESEARCH COUNCIL OF CANADA

Inventor： Nikola Pekas ,  Adam Johan Bergren

IPC: G06K7/10 ,  G06K19/077

Abstract: A tag detection system comprising a source for producing an interrogation signal having a first frequency; a harmonic radar tag comprising: an antenna structure; a tunneling junction electrically and integrally coupled to the antenna; and wherein the harmonic radar tag when stimulated by the interrogation signal having the first frequency, and the harmonic radar tag produces a response signal at a second frequency different from the first frequency.

公开(公告)号：US20240301381A1

公开(公告)日：2024-09-12

申请号：US18261854

申请日：2022-01-25

Applicant: National Research Council of Canada

Inventor： Traian SULEA ,  Yves DUROCHER

IPC: C12N9/48 ,  A61P31/14 ,  C12N15/63

CPC classification number: C12N9/485 ,  A61P31/14 ,  C12N15/63 ,  C12Y304/17023

Abstract: The present invention relates, in general, to polypeptides capable of neutralizing SARS-CoV-2 and providing ACE2 enzymatic activity, and uses of these polypeptides for treating disorders related coronaviral infections (COVID-19) and the accompanying acute respiratory distress syndrome (ARDS) and major organ injuries, and methods of making such molecules.

公开(公告)号：US12084510B2

公开(公告)日：2024-09-10

申请号：US16797364

申请日：2020-02-21

Applicant: GILEAD SCIENCES, INC. ,  NATIONAL RESEARCH COUNCIL OF CANADA

Inventor： Ilia Alexandre Tikhomirov ,  Maria L. Jaramillo ,  Maureen D. O'Connor-McCourt ,  Traian Sulea ,  Renald Gilbert ,  Bruno Gaillet ,  Jason Baardsnes ,  Myriam Banville ,  Suzanne Grothe

IPC: C07K16/30 ,  C07K16/28

CPC classification number: C07K16/30 ,  C07K16/2863 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/567

Abstract: Herein described are antibodies to epidermal growth factor receptor (EGER) having an EGER binding affinity that is sufficient to kill disease cells presenting EGFR at high density, but is insufficient for binding to normal cells. A therapeutic effect is thus achieved while avoiding adverse events that result from unintended binding to normal cells.

公开(公告)号：US12023734B2

公开(公告)日：2024-07-02

申请号：US17121004

申请日：2020-12-14

Applicant: NATIONAL RESEARCH COUNCIL OF CANADA

Inventor： Eric Irissou ,  Jean-Gabriel Legoux ,  Cristian Victor Cojocaru ,  Florin Ilinca ,  Sylvain Bournival

IPC: B05B7/14 ,  B22F10/364 ,  B22F10/38 ,  B22F10/85 ,  B22F12/13 ,  B22F12/43 ,  B22F12/49 ,  B22F12/53 ,  B22F12/90 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y40/10 ,  B33Y40/20 ,  B33Y50/02 ,  C23C24/08

CPC classification number: B22F10/85 ,  B22F10/364 ,  B22F10/38 ,  B22F12/13 ,  B22F12/43 ,  B22F12/49 ,  B22F12/53 ,  B22F12/90 ,  B33Y10/00 ,  B33Y30/00 ,  B33Y40/10 ,  B33Y40/20 ,  B33Y50/02 ,  C23C24/08 ,  B05B7/1486 ,  B22F2203/11

Abstract: A technique for improving cold spray deposition conditions for cold spray additive manufacture of parts involves providing an in-situ temperature feedback controller with a remote instantaneous temperature sensor supplying surface temperature measurements of the deposition surface, and a (preferably long pulse) laser for heating. Temperature feedback allows for control over deposition conditions yielding predictable deposition properties.

公开(公告)号：US20240204787A1

公开(公告)日：2024-06-20

申请号：US18431019

申请日：2024-02-02

Applicant: National Research Council of Canada

Inventor： Brent CARLSON

IPC: H03L7/099 ,  H03L7/14 ,  H03L7/24

CPC classification number: H03L7/0991 ,  H03L7/141 ,  H03L7/24

Abstract: A method for timing aperture synthesis arrays comprising the steps of: (a) coupling a plurality of independent crystal oscillators, each of the plurality of independent crystal oscillators having a unique output frequency; (b) digitally synchronizing the plurality of independent crystal oscillators in phase; (c) combining the unique output frequencies; and (d) obtaining a stable digital reference signal for timing at least one remote radio device of the aperture synthesis array.

公开(公告)号：US20240171369A1

公开(公告)日：2024-05-23

申请号：US18550594

申请日：2022-03-10

Applicant: National Research Council of Canada

Inventor： Brent Carlson

IPC: H04L7/02 ,  G06F1/06

CPC classification number: H04L7/02 ,  G06F1/06

Abstract: The present invention provides a method and system to correctly sample, at a central location, a signal at a second clock frequency from a remote antenna when the signal is at a first clock frequency. The present invention provides an improved method of incoherent clocking to correctly sample a signal from a remote antenna at a clock frequency of a central location, such as a central site of a radio telescope array. The signal contains a “tracer” which is related to the frequency of the remote antenna. The tracer phase is written into a dual-port memory at the first clock frequency and then read from the memory at the second clock frequency. The tracer phase is transferred across digital clock domains using Gray-doe methods so that phase coding errors do not occur.