公开(公告)号：US20240075084A1

公开(公告)日：2024-03-07

申请号：US18273295

申请日：2022-01-20

Applicant: Biomx Ltd.

Inventor： Eyal WEINSTOCK ,  Iddo Nadav WEINER ,  Maya KAHAN-HANUM ,  Efrat KHABRA ,  Noa BEN-YISHAI ,  Dana INBAR ,  Rotem EDGAR

IPC: A61K35/76 ,  A61P31/04 ,  C12N7/00

CPC classification number: A61K35/76 ,  A61P31/04 ,  C12N7/00 ,  C12N2795/10021 ,  C12N2795/10032

Abstract: A composition comprising at least two different strains of isolated bacteriophages, each capable of infecting a bacteria of the species Klebsiella pneumoniae, wherein at least one of said at least two different strains of isolated bacteriophages has a genomic nucleic acid sequence at least 90% identical to one of the nucleic acid sequence as set forth in SEQ ID NOs: 1-30. Uses thereof are also disclosed.

公开(公告)号：US20220152132A1

公开(公告)日：2022-05-19

申请号：US17436693

申请日：2020-03-06

Applicant: Keio University ,  Biomx Ltd.

Inventor： Kenya HONDA ,  Koji ATARASHI ,  Seiko NARUSHIMA ,  Efrat KHABRA ,  Hava BEN DAVID ,  Eyal WEINSTOCK ,  Yulia MATIUHIN ,  Naomi Bluma ZAK

IPC: A61K35/76 ,  A61P31/04

Abstract: Disclosed herein are bacteriophage compositions and therapeutic uses thereof. The disclosure also relates to bacteriophage that are capable of lysing Klebsiella bacterial strains, e.g., strains that are associated with inflammatory bowel disease, and thereby capable of modulating disease.