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公开(公告)号：US20100220330A1
公开(公告)日：2010-09-02
申请号：US12451547
申请日：2008-05-21
申请人： Boaz Ran , Tal Rosenzweig , Ariel G. Notcovich , Ariel Shemesh , Yochanan Uri , Michael Kanevsky , James W. Hillendahl , Barak Abraham Liraz
发明人： Boaz Ran , Tal Rosenzweig , Ariel G. Notcovich , Ariel Shemesh , Yochanan Uri , Michael Kanevsky , James W. Hillendahl , Barak Abraham Liraz
IPC分类号： G01N21/55
CPC分类号： G01N21/553
摘要： An SPR or other optical resonance based analysis system in which, light is provided at multiple angles to a specimen and then the light modified by the specimen is processed to select only some of the light. Optionally, the processing selects light at a particular incidence angle. Optionally, the detection is by imaging of the light on a 2D imager array.
摘要翻译： 基于SPR或其他基于光学共振的分析系统，其中以样品的多个角度提供光，然后处理由样本改变的光以仅选择一些光。 可选地，该处理以特定入射角选择光。 可选地，通过在2D成像器阵列上对光进行成像来进行检测。
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公开(公告)号：US08743367B2
公开(公告)日：2014-06-03
申请号：US12451547
申请日：2008-05-21
申请人： Boaz Ran , Tal Rosenzweig , Ariel G. Notcovich , Ariel Shemesh , Yochanan Uri , Michael Kanevsky , James W. Hillendahl , Barak Abraham Liraz
发明人： Boaz Ran , Tal Rosenzweig , Ariel G. Notcovich , Ariel Shemesh , Yochanan Uri , Michael Kanevsky , James W. Hillendahl , Barak Abraham Liraz
CPC分类号： G01N21/553
摘要： An SPR or other optical resonance based analysis system in which, light is provided at multiple angles to a specimen and then the light modified by the specimen is processed to select only some of the light. Optionally, the processing selects light at a particular incidence angle. Optionally, the detection is by imaging of the light on a 2D imager array.
摘要翻译： 基于SPR或其他基于光学共振的分析系统，其中以样品的多个角度提供光，然后处理由样本改变的光以仅选择一些光。 可选地，该处理以特定入射角选择光。 可选地，通过在2D成像器阵列上对光进行成像来进行检测。
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3.发明授权Biochemical assay detection in a liquid receptacle using a fiber optic exciter 有权使用光纤激光器在液体容器中进行生物化学检测公开(公告)号：US07218810B2
公开(公告)日：2007-05-15
申请号：US10252023
申请日：2002-09-19
CPC分类号： G01N21/253 , G01N21/6452 , G01N2021/6421 , G01N2021/6471 , G01N2021/6484
摘要： Biochemical assays that are performed in cuvettes and in the wells of multi-well plates and that utilize excitation and light emission as labels for detection are enhanced by an illumination and detection system that supplies excitation light through an optical fiber that transmits excitation light from an excitation light source to the cuvette or well. Emission light produced by the excitation is then collected by a collimating lens and converted to a signal that is compiled by conventional software for analysis. The optical fiber and collimating lens can either be on the same side of the receptacle (generally the open side) or on opposite sides, i.e., one above and the other below. When the optical fiber and the collimating lens are both on the open side of the receptacle, they are arranged such that the direction of travel of the excitation light and the direction along which the emission light is collected are not coaxial, and preferably both are at an acute angle to the axis normal to the mouth of the receptacle. Illumination systems are also disclosed in which a ultraviolet, visible, or near-infrared light source is optically coupled to an optical fiber.
摘要翻译： 通过照射和检测系统增强了在比色皿和多孔板的孔中进行的并且利用激发和发光作为检测标签的生化测定，该照明和检测系统通过透射激发光的光纤提供激发光 光源到比色皿或井。 由激发产生的发射光然后由准直透镜收集并转换为由常规软件编译的信号用于分析。 光纤和准直透镜可以位于插座的同一侧（通常为开放侧）或相对的两侧，即一个在另一个之上。 当光纤和准直透镜都在容器的开口侧时，它们被布置成使得激发光的行进方向和发射光被收集的方向不同轴，并且优选地两者都在 与垂直于容器口部的轴线呈锐角。 还公开了照明系统，其中紫外线，可见光或近红外光源光学耦合到光纤。
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公开(公告)号：US07376304B2
公开(公告)日：2008-05-20
申请号：US11521677
申请日：2006-09-14
CPC分类号： G01N21/6452 , G01N2021/6421 , G01N2021/6471 , G01N2021/6484
摘要： Biochemical assays of samples in receptacles, in gels, in blots, in arrays and the like, and that utilize excitation and light emission as labels for detection are enhanced by an illumination and detection system that supplies excitation light through an optical fiber that transmits excitation light from an excitation light source to the sample. Emission light produced by the excitation is then collected by a lens and converted to a signal that is compiled by conventional software for analysis. The optical fiber transfixes (passes through) the lens via a slot or other opening and is preferably offset from the center of the lens. The optical fiber and collecting lens can either be on the same side of the sample or on opposite sides, i.e., one above and the other below. The optical fiber and the light collecting lens are arranged such that the direction of travel of the excitation light and the direction along which the emission light is collected are not coaxial, and preferably both are at an acute angle to the axis normal to the mouth of the receptacle. Illumination systems are also disclosed in which a ultraviolet, visible, or near-infrared light source is optically coupled to an optical fiber.
摘要翻译： 通过照射和检测系统增强了在容器，凝胶，印迹，阵列等中的样品和利用激发和发光作为检测标签的样品的生物化学分析，其通过透射激发光的光纤提供激发光 从激发光源到样品。 然后由透镜产生的发射光被透镜收集并转换成由常规软件编译的信号用于分析。 光纤经由狭槽或其他开口将透镜经过（透过）透镜，并且优选地偏离透镜的中心。 光纤和收集透镜可以在样品的相同侧或者在相对的两侧，即一个在另一个之上。 光纤和聚光透镜被布置成使得激发光的行进方向和发射光被收集的方向不同轴，并且优选地两者都与垂直于嘴的轴成锐角 容器 还公开了照明系统，其中紫外线，可见光或近红外光源光学耦合到光纤。
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公开(公告)号：US07310462B2
公开(公告)日：2007-12-18
申请号：US11583409
申请日：2006-10-18
CPC分类号： G01N21/253 , G01N21/6452 , G01N2021/6421 , G01N2021/6471 , G01N2021/6484
摘要： Biochemical assays that are performed in cuvettes and in the wells of multi-well plates and that utilize excitation and light emission as labels for detection are enhanced by an illumination and detection system that supplies excitation light through an optical fiber that transmits excitation light from an excitation light source to the cuvette or well. Emission light produced by the excitation is then collected by a collimating lens and converted to a signal that is compiled by conventional software for analysis. The optical fiber and collimating lens can either be on the same side of the receptacle (generally the open side) or on opposite sides, i.e., one above and the other below. When the optical fiber and the collimating lens are both on the open side of the receptacle, they are arranged such that the direction of travel of the excitation light and the direction along which the emission light is collected are not coaxial, and preferably both are at an acute angle to the axis normal to the mouth of the receptacle. Illumination systems are also disclosed in which a ultraviolet, visible, or near-infrared light source is optically coupled to an optical fiber.
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公开(公告)号：US06754414B2
公开(公告)日：2004-06-22
申请号：US10252022
申请日：2002-09-19
IPC分类号： G02B600
CPC分类号： G01N21/6452 , G01N2021/6484 , Y10T436/11
摘要： Microarrays are imaged by an illumination and detection system that supplies excitation light through one or more optical fibers, each fiber transmitting excitation light from an excitation light source to a single spot in the microarray. Emission light from each spot is then collected by a collimating lens and converted to a signal that is compiled by conventional software into an image of the entire microarray. The optical fiber(s) and the collimating lens are arranged such that the direction of travel of the excitation light and the direction along which the emission light is collected are not coaxial, and preferably both are at an acute angle to the axis normal to the plane of the microarray.
摘要翻译： 微阵列通过照射和检测系统成像，该系统通过一个或多个光纤提供激发光，每个光纤将激发光从激发光源传输到微阵列中的单个点。 然后通过准直透镜收集每个斑点的发光，并将其转换为由常规软件编译成整个微阵列的图像的信号。 光纤和准直透镜被布置成使得激发光的行进方向和发射光被收集的方向不同轴，并且优选地两者都与垂直于该光束的轴成锐角 微阵列飞机。
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7.发明授权Rotating cylindrical magnetron structure with self supporting zinc alloy target 失效旋转圆柱形磁铁结构自支撑锌合金目标
公开(公告)号：US5171411A
公开(公告)日：1992-12-15
申请号：US703663
申请日：1991-05-21
CPC分类号： C22C18/00 , C23C14/3414
摘要： Alloys useful for preparing self-supporting cylindrical targets are provided. The alloys comprise zinc and one or more other metals chosen from the following: aluminum, bismuth, cerium, gadolinium, hafnium, niobium, silicon, tantalum, titanium, vanadium, yttrium, and zirconium. In one preferred embodiment, a zinc alloy with approximately 2% aluminum forms self-supporting cylindrical targets from which metal oxide films are prepared by reactive sputtering. The alloy oxide films are clear, transparent, non-absorbing, and optically functional.
摘要翻译： 提供了用于制备自支撑圆柱形靶的合金。 所述合金包含锌和一种或多种选自以下的金属：铝，铋，铈，钆，铪，铌，硅，钽，钛，钒，钇和锆。 在一个优选实施例中，具有约2％铝的锌合金形成自支撑圆柱形靶，通过反应溅射从其中制备金属氧化物膜。 合金氧化物膜是透明的，透明的，非吸收的和光学的。
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