专利检索 ap:("Boehringer Ingelheim Aminal Health USA Inc.") AND inv:"Joyce Pritchard" 第 1 页

1.

发明申请
Modified Marek's Disease Virus, and Vaccines Made Therefrom 审中-公开

公开(公告)号：US20190216920A1

公开(公告)日：2019-07-18

申请号：US16262774

申请日：2019-01-30

申请人： Boehringer Ingelheim Aminal Health USA Inc.

发明人： Joyce Pritchard , Teshome Mebatsion , Michel Bublot

IPC分类号： A61K39/255 , A61K39/12

CPC分类号： A61K39/255 , A61K39/12 , A61K2039/5254 , A61K2039/552 , C12N2710/16334 , C12N2740/13022 , C12N2830/60

摘要： The present invention provides an effective vaccine for Marek's disease, which may be prepared using a recombinant Marek's Disease Virus (MDV), strain CVI988, having been transformed with a foreign DNA construct that includes a long terminal repeat sequence of a reticuloendotheliosis virus. This safe viral agent elicits a highly protective immune response in a chicken against virulent MDV challenge without causing a significant degree of pathogenicity. Suitable formulations of the vaccine for use in chickens include an effective immunization dosage of this novel viral agent, along with a pharmaceutically acceptable carrier or diluent.