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公开(公告)号：US09427346B2
公开(公告)日：2016-08-30
申请号：US14201093
申请日：2014-03-07
Applicant: Boston Scientific Scimed, Inc.
Inventor： Thomas J. Herbst , Lynne E. Swanson
CPC classification number: A61M27/002 , A61F5/0013 , A61F5/0076 , A61M2210/1078 , A61M2210/1082 , A61M2210/12
Abstract: Methods and devices for redirecting at least a portion of a fluid from the mesenteric lymphatic system for elimination from the body are disclosed. The fluid may be redirected for elimination through the urinary system or redirected outside the body. The methods and devices disclosed may prevent a portion of a patient's dietary lipids, including cholesterol, from being absorbed, thereby reducing the total caloric load to assist in weight management.
Abstract translation: 公开了用于将来自肠系膜淋巴系统的至少一部分流体重新定向以从体内消除的方法和装置。 流体可以被重定向以通过泌尿系统消除或重定向到身体外部。 所公开的方法和装置可以防止患者的膳食脂质（包括胆固醇）的一部分被吸收，从而降低总热负荷以辅助体重管理。
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公开(公告)号：US20140276344A1
公开(公告)日：2014-09-18
申请号：US14201093
申请日：2014-03-07
Applicant: Boston Scientific Scimed, Inc.
Inventor： Thomas J. Herbst , Lynne E. Swanson
CPC classification number: A61M27/002 , A61F5/0013 , A61F5/0076 , A61M2210/1078 , A61M2210/1082 , A61M2210/12
Abstract: Methods and devices for redirecting at least a portion of a fluid from the mesenteric lymphatic system for elimination from the body are disclosed. The fluid may be redirected for elimination through the urinary system or redirected outside the body. The methods and devices disclosed may prevent a portion of a patient's dietary lipids, including cholesterol, from being absorbed, thereby reducing the total caloric load to assist in weight management.
Abstract translation: 公开了用于将来自肠系膜淋巴系统的至少一部分流体重新定向以从体内消除的方法和装置。 流体可以被重定向以通过泌尿系统消除或重定向到身体外部。 所公开的方法和装置可以防止患者的膳食脂质（包括胆固醇）的一部分被吸收，从而降低总热负荷以辅助体重管理。
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公开(公告)号：US20210370057A1
公开(公告)日：2021-12-02
申请号：US17404768
申请日：2021-08-17
Applicant: Boston Scientific Scimed Inc.
Inventor： Thomas J. Herbst , Craig Stolen
Abstract: A method for producing cardiomyocyte cells including implanting a substrate within a heart such that a first portion of the substrate is in physical contact with an endocardium and a second portion of the substrate is not in contact with the endocardium, maintaining the first portion of the substrate in contact with the endocardium for a time at least sufficient to form trabecular fibers extending between the endocardium and the second portion of the substrate, cutting away the trabecular fibers from the endocardium, cutting away the trabecular fibers from the substrate, and removing the trabecular fibers from the heart, wherein the trabecular fibers include cardiomyocyte cells.
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公开(公告)号：US10118034B2
公开(公告)日：2018-11-06
申请号：US15239565
申请日：2016-08-17
Applicant: Boston Scientific Scimed Inc.
Inventor： Thomas J. Herbst , Craig Stolen
Abstract: A method for producing cardiomyocyte cells including implanting a substrate within a heart such that a first portion of the substrate is in physical contact with an endocardium and a second portion of the substrate is not in contact with the endocardium, maintaining the first portion of the substrate in contact with the endocardium for a time at least sufficient to form trabecular fibers extending between the endocardium and the second portion of the substrate, cutting away the trabecular fibers from the endocardium, cutting away the trabecular fibers from the substrate, and removing the trabecular fibers from the heart, wherein the trabecular fibers include cardiomyocyte cells.
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公开(公告)号：US12172008B2
公开(公告)日：2024-12-24
申请号：US17404768
申请日：2021-08-17
Applicant: Boston Scientific Scimed Inc.
Inventor： Thomas J. Herbst , Craig Stolen
Abstract: A method for producing cardiomyocyte cells including implanting a substrate within a heart such that a first portion of the substrate is in physical contact with an endocardium and a second portion of the substrate is not in contact with the endocardium, maintaining the first portion of the substrate in contact with the endocardium for a time at least sufficient to form trabecular fibers extending between the endocardium and the second portion of the substrate, cutting away the trabecular fibers from the endocardium, cutting away the trabecular fibers from the substrate, and removing the trabecular fibers from the heart, wherein the trabecular fibers include cardiomyocyte cells.
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Patent Agency Ranking
公开(公告)号：US11116969B2
公开(公告)日：2021-09-14
申请号：US16148838
申请日：2018-10-01
Applicant: Boston Scientific Scimed Inc.
Inventor： Thomas J. Herbst , Craig Stolen
Abstract: A method for producing cardiomyocyte cells including implanting a substrate within a heart such that a first portion of the substrate is in physical contact with an endocardium and a second portion of the substrate is not in contact with the endocardium, maintaining the first portion of the substrate in contact with the endocardium for a time at least sufficient to form trabecular fibers extending between the endocardium and the second portion of the substrate, cutting away the trabecular fibers from the endocardium, cutting away the trabecular fibers from the substrate, and removing the trabecular fibers from the heart, wherein the trabecular fibers include cardiomyocyte cells.
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公开(公告)号：US20180147409A1
公开(公告)日：2018-05-31
申请号：US15712542
申请日：2017-09-22
Applicant: Boston Scientific Scimed Inc.
Inventor： Thomas J. Herbst , Craig M. Stolen , Candace A. Rhodes
Abstract: A device for producing a trabecular fiber within a ventricle of a heart. The device includes a substrate and a first tissue anchor connected to the substrate. The substrate is formed of a non-rigid material.
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公开(公告)号：US10773077B2
公开(公告)日：2020-09-15
申请号：US15712542
申请日：2017-09-22
Applicant: Boston Scientific Scimed Inc.
Inventor： Thomas J. Herbst , Craig M. Stolen , Candace A. Rhodes
Abstract: A device for producing a trabecular fiber within a ventricle of a heart. The device includes a substrate and a first tissue anchor connected to the substrate. The substrate is formed of a non-rigid material.
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公开(公告)号：US10293146B2
公开(公告)日：2019-05-21
申请号：US15222053
申请日：2016-07-28
Applicant: Boston Scientific Scimed, Inc.
Inventor： Thomas J. Herbst , Lynne E. Swanson
Abstract: Methods and devices for redirecting at least a portion of a fluid from the mesenteric lymphatic system for elimination from the body are disclosed. The fluid may be redirected for elimination through the urinary system or redirected outside the body. The methods and devices disclosed may prevent a portion of a patient's dietary lipids, including cholesterol, from being absorbed, thereby reducing the total caloric load to assist in weight management.
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公开(公告)号：US20170050018A1
公开(公告)日：2017-02-23
申请号：US15239565
申请日：2016-08-17
Applicant: Boston Scientific Scimed Inc.
Inventor： Thomas J. Herbst , Craig Stolen
CPC classification number: A61N1/326 , A61N1/056 , A61N1/0573 , A61N1/205 , C12N5/0657
Abstract: A method for producing cardiomyocyte cells including implanting a substrate within a heart such that a first portion of the substrate is in physical contact with an endocardium and a second portion of the substrate is not in contact with the endocardium, maintaining the first portion of the substrate in contact with the endocardium for a time at least sufficient to form trabecular fibers extending between the endocardium and the second portion of the substrate, cutting away the trabecular fibers from the endocardium, cutting away the trabecular fibers from the substrate, and removing the trabecular fibers from the heart, wherein the trabecular fibers include cardiomyocyte cells.
Abstract translation: 一种用于产生心肌细胞的方法，包括在心脏内植入衬底，使得衬底的第一部分与心内膜物理接触，并且衬底的第二部分不与心内膜接触，保持衬底的第一部分 与心内膜接触至少足以形成在心内膜和基底的第二部分之间延伸的小梁纤维的时间，将小梁纤维从心内膜切除，从基底切除小梁纤维，并移除小梁纤维 从心脏，其中小梁纤维包括心肌细胞。
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