Electric field application for single shot cardiac ablation by irreversible electroporation

    公开(公告)号:US12268437B2

    公开(公告)日:2025-04-08

    申请号:US17381953

    申请日:2021-07-21

    Abstract: Disclosed herein are apparatus, systems, and methods for ablating tissue in a patient by electroporation. Embodiments generally include an ablation catheter having a hand, a shaft, and an electroporation electrode arrangement. The shaft has a distal end and defines a longitudinal axis of the ablation catheter. The electroporation electrode arrangement is at the distal end of the shaft and is configured to generate a multidirectional electric field when at least one pulse sequence is delivered thereto. The multidirectional electric field includes at least two of the following directions relative to the longitudinal axis: generally axial, circumferential, and transverse. The electroporation electrode arrangement is configured to operatively couple to an electroporation generator that is configured to generate the at least one pulse sequence and is configured to receive the at least one pulse sequence from the electroporation generator.

    Catheter and Method for Focal Cardiac Ablation by Irreversible Electroporation

    公开(公告)号:US20220015826A1

    公开(公告)日:2022-01-20

    申请号:US17378219

    申请日:2021-07-16

    Abstract: A catheter for focal cardiac ablation by irreversible electroporation includes a flexible catheter body, a plurality of tines disposed at a distal end of the catheter body, a flexible shaft, a return electrode, and an electrical conductor. The plurality of tines are formed of an electrically conductive material and configured to deploy from a lumen at the distal end of the catheter body. Each tine of the plurality of tines is configured to self-bias from a linear configuration within the lumen to a curved configuration when deployed from the lumen. The shaft is mechanically and electrically coupled to the plurality of tines. The shaft is configured to deploy the tines from the lumen when the shaft is moved toward the distal end of the catheter body. The return electrode is disposed on an outer surface of the catheter body. The electrical conductor is electrically coupled to the return electrode.

    Electric Field Application for Single Shot Cardiac Ablation by Irreversible Electroporation

    公开(公告)号:US20220022952A1

    公开(公告)日:2022-01-27

    申请号:US17381953

    申请日:2021-07-21

    Abstract: Disclosed herein are apparatus, systems, and methods for ablating tissue in a patient by electroporation. Embodiments generally include an ablation catheter having a hand, a shaft, and an electroporation electrode arrangement. The shaft has a distal end and defines a longitudinal axis of the ablation catheter. The electroporation electrode arrangement is at the distal end of the shaft and is configured to generate a multidirectional electric field when at least one pulse sequence is delivered thereto. The multidirectional electric field includes at least two of the following directions relative to the longitudinal axis: generally axial, circumferential, and transverse. The electroporation electrode arrangement is configured to operatively couple to an electroporation generator that is configured to generate the at least one pulse sequence and is configured to receive the at least one pulse sequence from the electroporation generator.

    Point Pulsed Field Ablation Catheter

    公开(公告)号:US20220378502A1

    公开(公告)日:2022-12-01

    申请号:US17825456

    申请日:2022-05-26

    Abstract: Various aspects of the present disclosure are directed towards apparatuses, systems and methods that may include an electroporation ablation device. The electroporation ablation device may include a shaft defining a longitudinal axis and an electrode assembly including a first pair of electrodes having a first electrode and a second electrode, and a second pair of electrodes disposed adjacent to the first pair of electrodes and having a third and a fourth electrode. In some embodiments, the first electrode has a first edge portion, and a first side view of the first edge portion along the longitudinal axis is rounded at a first corner.

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