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Patent Agency Ranking
公开(公告)号：US11273328B2
公开(公告)日：2022-03-15
申请号：US16328653
申请日：2018-03-02
Applicant: Brainlab AG
Inventor： Stefan Schell , Claus Promberger
IPC: A61N5/10
Abstract: A computer-implemented medical method of irradiation treatment planning is provided. Therein, an initial coverage volume for a planning target volume, which is to be irradiated in an irradiation treatment with a prescribed dose, is provided. Further, at least one constraint indicative of an allowed dose for an organ at risk is provided. Applying an initial irradiation treatment plan, an organ dose deposited in at least a partial volume of the organ at risk is calculated. Based on comparing the organ dose to the at least one constraint, an amount of violation is determined. Taking into account the determined amount of violation, a reduction coverage volume is calculated for the planning target volume and a virtual planning object is generated based on changing a volume of the organ at risk, such that an overlap region of the virtual planning object and the planning target volume corresponds to the reduction coverage volume. By removing at least a part of the overlap region from the planning target volume, an optimized planning target volume is generated.
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公开(公告)号：US20200069972A1
公开(公告)日：2020-03-05
申请号：US16328653
申请日：2018-03-02
Applicant: Brainlab AG
Inventor： Stefan Schell , Claus Promberger
IPC: A61N5/10
Abstract: A computer-implemented medical method of irradiation treatment planning is provided. Therein, an initial coverage volume (118) for a planning target volume (116), which is to be irradiated in an irradiation treatment with a prescribed dose, is provided. Further, at least one constraint (106, 110) indicative of an allowed dose for an organ at risk (120) is provided. Applying an initial irradiation treatment plan, an organ dose deposited in at least a partial volume of the organ at risk (120) is calculated. Based on comparing the organ dose to the at least one constraint (106, 110), an amount of violation is determined. Taking into account the determined amount of violation, a reduction coverage volume is calculated for the planning target volume (116) and a virtual planning object (122) is generated based on changing a volume of the organ at risk (120), such that an overlap region (124) of the virtual planning object (122) and the planning target volume (116) corresponds to the reduction coverage volume. By removing at least a part of the overlap region (124) from the planning target volume (116), an optimized planning target volume (132) is generated.
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公开(公告)号：US10105553B2
公开(公告)日：2018-10-23
申请号：US14921363
申请日：2015-10-23
Applicant: Brainlab AG
Inventor： Pascal Bertram , Claus Promberger , Thomas Flurschuetz
Abstract: A method for generating planning data or control data for a radiation treatment, comprising the following steps: acquiring segmented data of an object which contains a treatment volume and a non-treatment volume; modelling at least some or all of the volume or surface of the treatment volume as a source of light or rays exhibiting a predefined or constant initial intensity; modelling the non-treatment volume as comprising volumetric elements or voxels which each exhibit an individually assigned feature or attenuation or transparency value (tmin≤t≤tmax) for the light or rays which feature is assigned to the light or ray or which attenuation or transparency maintains or reduces the intensity of the light or ray as it passes through the respective volumetric element or voxel, wherein the feature or attenuation or transparency value is individually assigned to each volumetric element or voxel of the non-treatment volume; defining a map surface which surrounds the treatment volume or the object; calculating an accumulated intensity value for points or areas on the map surface, the accumulated intensity being the sum of the intensities of all the rays which exhibit the predefined or constant initial intensity and are emitted from the volume or surface of the treatment volume and reach a respective point on the map surface preferably by following a straight line, wherein if the ray passes through a non-treatment volume or voxel, the intensity of the respective ray is reduced or attenuated by a factor which is determined by the individual feature or attenuation or transparency value of the respective non-treatment volume or voxel; and generating an intensity distribution on the map surface using the calculated accumulated intensities.
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公开(公告)号：US20230030380A1
公开(公告)日：2023-02-02
申请号：US17783675
申请日：2019-12-10
Applicant: Brainlab AG
Inventor： Stefan VILSMEIER , Claus Promberger
Abstract: Provided are a method and apparatus for determining displacement of an internal object disposed in a patient's body. The method includes positioning an arrangement of electrodes of a capacitive sensor adjacent to a patient's body part, such that each electrode is spaced apart from the body part, wherein the body part at least partly encloses the internal object of the patient. Providing, with the capacitive sensor, a plurality of sensor signals, wherein each sensor signal is indicative of a capacitance in a vicinity of at least one electrode of the arrangement of electrodes, determining a set of capacitance values for at least a subset of the electrodes of the arrangement of electrodes based on processing the plurality of sensor signals, and determining a displacement of the internal object with respect to the body part based on comparing the determined set of capacitance values with a set of reference capacitance values.
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公开(公告)号：US10143858B2
公开(公告)日：2018-12-04
申请号：US15560737
申请日：2015-10-14
Applicant: Brainlab AG
Inventor： Stefan Schell , Claus Promberger , Robert Grummt , Andreas Schaetti
Abstract: Disclosed is a computer-implemented medical data processing method for determining a dose distribution for use in a medical procedure involving irradiation of an anatomical structure of a patient's body with ionizing radiation. A processor acquires medical image data describing a medical image of the anatomical structure. The processor acquires dose distribution data describing an irradiation dose distribution spatially defined in the reference system of the medical image of the anatomical structure. Prioritization data is determined that describes, for each image unit of the medical image describing non-target tissue, a priority of that image unit for consideration during an optimization of the irradiation dose distribution described by the dose distribution data. Based on the dose distribution data and the prioritization data, changed dose distribution data is determined that describes a changed irradiation dose distribution spatially defined in the reference system of the medical image of the anatomical structure.
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