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1.发明申请Fluorescent Methods and Materials for Directed Biomarker Signal Amplification 有权用于定向生物标志物信号放大的荧光方法和材料公开(公告)号：US20120028828A1
公开(公告)日：2012-02-02
申请号：US13195747
申请日：2011-08-01
CPC分类号： G01N33/582 , C08G61/02 , C08G61/12 , C08G61/128 , C08G2261/3142 , C08G2261/3221 , C08G2261/3241 , C08G2261/3246 , C08G2261/522 , C08G2261/78 , C08G2261/94 , G01N33/542 , H01L51/0039 , Y10T436/13
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
摘要翻译： 提供了包括用于鉴定靶生物分子的多色素和/或多重色团合成物的方法和组合物。 传感器生物分子，例如抗体可以共价连接到多色素。 另外，信号发色团可以共价连接到多重色素。 这种布置使得信号发色团能够在多重色谱激发时能够从多重色淀中接收能量。 由于传感器生物分子能够与目标生物分子相互作用，多重色谱和/或多重色谱复合物可为目标生物分子提供增强的检测信号。
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2.发明授权Fluorescent methods and materials for directed biomarker signal amplification 有权用于定向生物标记信号放大的荧光方法和材料公开(公告)号：US08802450B2
公开(公告)日：2014-08-12
申请号：US13195747
申请日：2011-08-01
CPC分类号： G01N33/582 , C08G61/02 , C08G61/12 , C08G61/128 , C08G2261/3142 , C08G2261/3221 , C08G2261/3241 , C08G2261/3246 , C08G2261/522 , C08G2261/78 , C08G2261/94 , G01N33/542 , H01L51/0039 , Y10T436/13
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
摘要翻译： 提供了包括用于鉴定靶生物分子的多色素和/或多重色团合成物的方法和组合物。 传感器生物分子，例如抗体可以共价连接到多色素。 另外，信号发色团可以共价连接到多重色素。 这种布置使得信号发色团能够在多重色谱激发时能够从多重色淀中接收能量。 由于传感器生物分子能够与目标生物分子相互作用，多重色谱和/或多重色谱复合物可为目标生物分子提供增强的检测信号。
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3.发明授权Fluorescent methods and materials for directed biomarker signal amplification 有权用于定向生物标记信号放大的荧光方法和材料公开(公告)号：US08354239B2
公开(公告)日：2013-01-15
申请号：US13195736
申请日：2011-08-01
IPC分类号： G01N33/53 , G01N33/533 , G01N21/76
CPC分类号： G01N33/582 , C08G61/02 , C08G61/12 , C08G61/128 , C08G2261/3142 , C08G2261/3221 , C08G2261/3241 , C08G2261/3246 , C08G2261/522 , C08G2261/78 , C08G2261/94 , G01N33/542 , H01L51/0039 , Y10T436/13
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
摘要翻译： 提供了包括用于鉴定靶生物分子的多色素和/或多重色团合成物的方法和组合物。 传感器生物分子，例如抗体可以共价连接到多色素。 另外，信号发色团可以共价连接到多重色素。 这种布置使得信号发色团能够在多重色谱激发时能够从多重色淀中接收能量。 由于传感器生物分子能够与目标生物分子相互作用，多重色谱和/或多重色谱复合物可为目标生物分子提供增强的检测信号。
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4.发明授权Fluorescent methods and materials for directed biomarker signal amplification 有权用于定向生物标记信号放大的荧光方法和材料公开(公告)号：US08158444B2
公开(公告)日：2012-04-17
申请号：US11868870
申请日：2007-10-08
IPC分类号： G01N33/533 , G01N21/76 , G01N33/53
CPC分类号： G01N33/582 , C08G61/02 , C08G61/12 , C08G61/128 , C08G2261/3142 , C08G2261/3221 , C08G2261/3241 , C08G2261/3246 , C08G2261/522 , C08G2261/78 , C08G2261/94 , G01N33/542 , H01L51/0039 , Y10T436/13
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
摘要翻译： 提供了包括用于鉴定靶生物分子的多色素和/或多重色团合成物的方法和组合物。 传感器生物分子，例如抗体可以共价连接到多色素。 另外，信号发色团可以共价连接到多重色素。 这种布置使得信号发色团能够在多重色谱激发时能够从多重色淀中接收能量。 由于传感器生物分子能够与目标生物分子相互作用，多重色谱和/或多重色谱复合物可为目标生物分子提供增强的检测信号。
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公开(公告)号：US20120029155A1
公开(公告)日：2012-02-02
申请号：US13195736
申请日：2011-08-01
IPC分类号： C08G73/06
CPC分类号： G01N33/582 , C08G61/02 , C08G61/12 , C08G61/128 , C08G2261/3142 , C08G2261/3221 , C08G2261/3241 , C08G2261/3246 , C08G2261/522 , C08G2261/78 , C08G2261/94 , G01N33/542 , H01L51/0039 , Y10T436/13
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
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6.发明申请Fluorescent Methods and Materials for Directed Biomarker Signal Amplification 有权用于定向生物标志物信号放大的荧光方法和材料公开(公告)号：US20080293164A1
公开(公告)日：2008-11-27
申请号：US11868870
申请日：2007-10-08
IPC分类号： G01N33/536 , C08G63/48
CPC分类号： G01N33/582 , C08G61/02 , C08G61/12 , C08G61/128 , C08G2261/3142 , C08G2261/3221 , C08G2261/3241 , C08G2261/3246 , C08G2261/522 , C08G2261/78 , C08G2261/94 , G01N33/542 , H01L51/0039 , Y10T436/13
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
摘要翻译： 提供了包括用于鉴定靶生物分子的多色素和/或多重色团合成物的方法和组合物。 传感器生物分子，例如抗体可以共价连接到多色素。 另外，信号发色团可以共价连接到多重色素。 这种布置使得信号发色团能够在多重色谱激发时能够从多重色淀中接收能量。 由于传感器生物分子能够与目标生物分子相互作用，多重色谱和/或多重色谱复合物可为目标生物分子提供增强的检测信号。
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