摘要:
A method of modifying properties of intrinsic tissue of an organ is provided. The method includes providing an organ, where a first electrode is disposed proximal to the organ first end. The first electrode has a surface area and insulator. A second electrode is disposed opposite the first electrode, where the organ is disposed between the first electrode and the second electrode. The second electrode has surface area and surface insulator. An organ-shaping device is provided that is disposed on the organ between the electrodes, where the organ-shaping device deforms the organ middle section along at least one lateral direction between the electrodes. An electric current is provided between the first second electrodes, where a current density gradient is provided by the electrode surface areas and the deformed organ middle section, and the properties of the intrinsic muscle tissue are modified according to the current density gradient.
摘要:
A method of modifying properties of intrinsic tissue of an organ is provided. The method includes providing an organ, where a first electrode is disposed proximal to the organ first end. The first electrode has a surface area and insulator. A second electrode is disposed opposite the first electrode, where the organ is disposed between the first electrode and the second electrode. The second electrode has surface area and surface insulator. An organ-shaping device is provided that is disposed on the organ between the electrodes, where the organ-shaping device deforms the organ middle section along at least one lateral direction between the electrodes. An electric current is provided between the first second electrodes, where a current density gradient is provided by the electrode surface areas and the deformed organ middle section, and the properties of the intrinsic muscle tissue are modified according to the current density gradient.
摘要:
The present invention relates generally to dynamic support devices, methods of providing dynamic support to target tissues, and kits comprising these devices. These devices may have particular utility in providing support to the urethra. The dynamic support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one support member, where the device capable of assuming a first configuration and a second configuration. The dynamic support devices may be configured to support a target tissue when the device is in its second configuration. The support member may comprise one or more rotating components, one or more deformable components, one or more sliding components, or a combination thereof.
摘要:
The present invention relates generally to dynamic support devices, methods of providing dynamic support to target tissues, and kits comprising these devices. These devices may have particular utility in providing support to the urethra. The dynamic support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one support member, where the device capable of assuming a first configuration and a second configuration. The dynamic support devices may be configured to support a target tissue when the device is in its second configuration. The support member may comprise one or more rotating components, one or more deformable components, one or more sliding components, or a combination thereof.
摘要:
The present invention relates generally to dynamic and/or adjustable support devices, methods of providing dynamic and/or adjustable support to target tissues, and kits comprising these devices. These devices may have particular utility in providing support to the urethra. The dynamic support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one expandable member capable of assuming an unexpanded configuration and an expanded configuration. The adjustable support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one shape-changing portion that is capable of assuming first and second configurations, each with different shapes. Additionally, the dynamic support devices may comprise features of the adjustable support devices, and vice versa.
摘要:
The present invention relates generally to dynamic and/or adjustable support devices, methods of providing dynamic and/or adjustable support to target tissues, and kits comprising these devices. These devices may have particular utility in providing support to the urethra. The dynamic support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one expandable member capable of assuming an unexpanded configuration and an expanded configuration. The adjustable support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one shape-changing portion that is capable of assuming first and second configurations, each with different shapes. Additionally, the dynamic support devices may comprise features of the adjustable support devices, and vice versa.
摘要:
A device completely disposable within a bodily lumen of a patient and for controlling flow through the bodily lumen having a device body having a proximal end, a distal end and a device lumen within the device body extending from the proximal end to the distal end and a fixation element extending from the outer wall of device body adapted and configured to engage with the wall of the bodily lumen. The device body is adapted and configured to move from a position where the device lumen blocks flow through the bodily lumen to a position where the device lumen allows flow through the bodily lumen. In other configurations, there are one or more valves within the device lumen adapted and configured to move between a position to block flow through the bodily lumen and a position to allow flow through the bodily lumen. There is also a method for implanting a device within a body lumen by placing a device having a device body and fixation elements extending from the device body on a catheter and then dilating the body lumen such that the device body and the fixation elements may advance through the dilated body lumen without the fixation elements engaging the wall of the body lumen. Next, advancing the device to an implant site within the body lumen and then engaging the walls of the body lumen with the fixation elements.
摘要:
The invention relates to a device and method to counteract the deposition of material on devices that dwell in the urinary tract and which include an operably connected motion-inducing actuator. Counteracting material deposition includes impeding or preventing deposition as well as diminishing extant deposition. Deposition is counteracted by moving the device with the motion-inducing actuator; motion may include movement of the device with respect to its position within the urinary tract, as well as deformational or vibrational movement of the device. Embodiments of the device receive energy from a source either by physical or wireless connection. In some embodiments the motion-inducing actuator is integral with the structure of the device, in other embodiments the actuator is a separate structure. In still other embodiments, the device receives energy directly, without intervention of an actuator. In some of these latter embodiments, the device may include an energy focusing element.