公开(公告)号：US07074435B2

公开(公告)日：2006-07-11

申请号：US10345197

申请日：2003-01-16

申请人： Byung-Wook Cho ,  Mirim Jin ,  Hyung-Jin Jung ,  Sung-Seup Shin ,  Sunyoung Kim ,  Hyang Jeon ,  Jin-Hwan Oh ,  Hae-Kwan Eo ,  Bongcheol Kim

发明人： Byung-Wook Cho ,  Mirim Jin ,  Hyung-Jin Jung ,  Sung-Seup Shin ,  Sunyoung Kim ,  Hyang Jeon ,  Jin-Hwan Oh ,  Hae-Kwan Eo ,  Bongcheol Kim

IPC分类号： A61K35/78

CPC分类号： A61K36/00 ,  A61K2300/00

摘要： The present invention is related to pharmaceutical composition essentially comprising herbal extract of Chaenomelis Fructus, Achyranthis Radix, Acanthopanax, Phlomidis Radix, Gentianae Radix, Clematidis Radix, and additionally comprising herbal extract selected from group consisting of Angelicae Radix, Cnidii Rhizoma, Gastrodiae Rhizoma, Safflower, Cinnamomi Cortex, Job's tear, Aurantii nobilis Pericapium, Ledebouriellae Radix, Lonicera japonica, Akebiae caulis, Caragana chamlagu, Licorice root, Notopterygium incisum, Persicae semen, Eucommia ulmoides, Atractylodes Rhizoma, Torilis japonica according to the need for the prevention and treatment of arthritic diseases and methods of using the above extracts and composition as potent anti-inflammatory and anti-arthritic agents.

公开(公告)号：USD638031S1

公开(公告)日：2011-05-17

申请号：US29376780

申请日：2010-10-12

申请人： Joo-Yeon Lee ,  Jin-Hwan Oh ,  Seung-Ju Yuk ,  Hyun-Soo Kim

设计人： Joo-Yeon Lee ,  Jin-Hwan Oh ,  Seung-Ju Yuk ,  Hyun-Soo Kim

公开(公告)号：US07365192B2

公开(公告)日：2008-04-29

申请号：US10519519

申请日：2002-11-23

申请人： Youl Her ,  Jin-Hwan Oh

发明人： Youl Her ,  Jin-Hwan Oh

IPC分类号： C07H1/00 ,  C07H3/00 ,  C08B37/00 ,  C07C211/00

CPC分类号： C07F9/54 ,  C07C213/00 ,  C07C2601/10 ,  C07C215/44

摘要： The present invention provides a preparation method of valienamine from acarbose or acarbose derivatives using organic acid TFA (trifluoroacetic acid). By using the method of the present invention, valienamine, the core precursor of voglibose which is a strong retardant of α-glucosidase and which is used for the cure of diabetes, can be produced in large quantities by using selective hydrolysis from acarbose or acarbose derivatives using TFA.

摘要翻译： 本发明提供了使用有机酸TFA（三氟乙酸）从阿卡波糖或阿卡波糖衍生物制备的胺甲胺的制备方法。 通过使用本发明的方法，可以通过使用来自阿卡波糖或阿卡波糖衍生物的选择性水解，大量生产作为α-葡萄糖苷酶的强阻滞剂的伏格列波胶的核心前体，可用于治疗糖尿病 使用TFA。

公开(公告)号：US20050272674A1

公开(公告)日：2005-12-08

申请号：US10519519

申请日：2002-11-23

申请人： Youl Her ,  Jin-Hwan Oh

发明人： Youl Her ,  Jin-Hwan Oh

IPC分类号： C07C213/00 ,  A61K31/704 ,  C07B61/00 ,  C07C29/14 ,  C07C209/62 ,  C07C215/44 ,  C07F9/54

CPC分类号： C07F9/54 ,  C07C213/00 ,  C07C2601/10 ,  C07C215/44

摘要： The present invention provides a preparation method of valienamine from acarbose or acarbose derivatives using organic acid TFA (trifluoroacetic acid). By using the method of the present invention, valienamine, the core precursor of voglibose which is a strong retardant of α-glucosidase and which is used for the cure of diabetes, can be produced in large quantities by using selective hydrolysis from acarbose or acarbose derivatives using TFA.

摘要翻译： 本发明提供了使用有机酸TFA（三氟乙酸）从阿卡波糖或阿卡波糖衍生物制备的胺甲胺的制备方法。 通过使用本发明的方法，可以通过使用来自阿卡波糖或阿卡波糖衍生物的选择性水解，大量生产作为α-葡萄糖苷酶的强阻滞剂的伏格列波胶的核心前体，可用于治疗糖尿病 使用TFA。