专利检索 ap:("C-BIOMEX CO., LTD.") AND inv:"Seo Hyun Park" 第 1 页

1.

发明公开
PEPTIDE LIGAND TARGETING CARBONIC ANHYDRASE IX, PEPTIDE CONSTRUCT COMPRISING SAME, AND USES THEREOF 审中-公开

公开(公告)号：US20240327464A1

公开(公告)日：2024-10-03

申请号：US18289027

申请日：2023-02-10

申请人： C-BIOMEX CO., LTD.

发明人： Song Gil Lee , Hye Sook Ha , Jin Hwi Park , Se Won Kim , Yoo Joung Oh , Seo Hyun Park , Shin Young Park , Jun Hoe Cha

IPC分类号： C07K7/64 , A61K47/64 , A61K49/00 , A61K51/08 , A61P35/00 , C07K1/107

CPC分类号： C07K7/64 , A61K47/64 , A61K49/0056 , A61K51/088 , A61P35/00 , C07K1/1077

摘要： The present invention relates to a peptide ligand that specifically binds to carbonic anhydrase IX (CAIX), a peptide construct comprising the ligand, and a use thereof. The CAIX-binding peptide ligand of the present invention includes D-amino acids, so it is stable in the body and has high binding specificity to CAIX. And the linear or cyclic CAIX-binding peptide construct comprising the ligand can bind to CAIX with high affinity in the body. Therefore, it is useful for diagnosis, prevention, suppression or treatment of diseases mediated by CAIX.