公开(公告)号：US20240307384A1

公开(公告)日：2024-09-19

申请号：US18593518

申请日：2024-03-01

申请人： CalciMedica, Inc.

发明人： Gonul VELICELEBI ,  Kenneth STAUDERMAN ,  Michael DUNN ,  Jack ROOS

IPC分类号： A61K31/497 ,  A61K31/415 ,  A61K31/4155 ,  A61K31/421 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/485 ,  A61K31/506 ,  A61K45/06 ,  A61P1/18 ,  C07D401/04 ,  C07D405/04 ,  C07D413/14 ,  C07D417/10 ,  C07D417/14 ,  C07D491/04

CPC分类号： A61K31/497 ,  A61K31/415 ,  A61K31/4155 ,  A61K31/421 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/485 ,  A61K31/506 ,  A61K45/06 ,  A61P1/18 ,  C07D401/04 ,  C07D405/04 ,  C07D413/14 ,  C07D417/10 ,  C07D417/14 ,  C07D491/04 ,  Y02A50/30

摘要： Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may be used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.

公开(公告)号：US20220265645A1

公开(公告)日：2022-08-25

申请号：US17203547

申请日：2021-03-16

申请人： CalciMedica, Inc.

发明人： Gonul VELICELEBI ,  Kenneth STAUDERMAN ,  Michael DUNN ,  Jack ROOS

IPC分类号： A61K31/497 ,  A61K45/06 ,  A61K31/415 ,  A61K31/427 ,  A61K31/485 ,  C07D405/04 ,  C07D417/14 ,  A61K31/444 ,  A61K31/4155 ,  A61K31/506 ,  C07D401/04 ,  A61K31/421 ,  C07D417/10 ,  A61K31/4439 ,  C07D491/04 ,  C07D413/14 ,  A61P1/18

摘要： Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may he used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.

公开(公告)号：US20180235958A1

公开(公告)日：2018-08-23

申请号：US15553531

申请日：2016-02-26

申请人： CALCIMEDICA, INC.

发明人： Gonul VELICELEBI ,  Kenneth STAUDERMAN ,  Michael DUNN ,  Jack ROOS

IPC分类号： A61K31/497 ,  A61K31/415 ,  A61K31/427 ,  A61K31/485 ,  A61K45/06 ,  A61P1/18

CPC分类号： A61K31/497 ,  A61K31/415 ,  A61K31/4155 ,  A61K31/421 ,  A61K31/427 ,  A61K31/4439 ,  A61K31/444 ,  A61K31/485 ,  A61K31/506 ,  A61K45/06 ,  A61P1/18 ,  C07D401/04 ,  C07D405/04 ,  C07D413/14 ,  C07D417/10 ,  C07D417/14 ,  C07D491/04 ,  Y02A50/478 ,  Y02A50/481 ,  A61K2300/00

摘要： Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may be used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.

公开(公告)号：US20220000863A1

公开(公告)日：2022-01-06

申请号：US17472422

申请日：2021-09-10

申请人： CalciMedica, Inc.

发明人： Gonul VELICELEBI ,  Kenneth STAUDERMAN ,  Michael DUNN ,  Jack ROOS

IPC分类号： A61K31/497 ,  A61K45/06 ,  A61K31/415 ,  A61K31/427 ,  A61K31/485 ,  C07D405/04 ,  C07D417/14 ,  A61K31/444 ,  A61K31/4155 ,  A61K31/506 ,  C07D401/04 ,  A61K31/421 ,  C07D417/10 ,  A61K31/4439 ,  C07D491/04 ,  C07D413/14 ,  A61P1/18

摘要： Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may be used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.

公开(公告)号：US20210038597A1

公开(公告)日：2021-02-11

申请号：US17077818

申请日：2020-10-22

申请人： CalciMedica, Inc.

发明人： Gonul VELICELEBI ,  Kenneth STAUDERMAN ,  Michael DUNN ,  Jack ROOS

IPC分类号： A61K31/497 ,  A61K31/415 ,  A61K31/427 ,  A61K31/485 ,  C07D405/04 ,  C07D417/14 ,  A61K31/444 ,  A61K31/4155 ,  A61K31/506 ,  C07D401/04 ,  A61K31/421 ,  C07D417/10 ,  A61K31/4439 ,  C07D491/04 ,  C07D413/14 ,  A61P1/18 ,  A61K45/06

摘要： Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may be used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.

公开(公告)号：US20200368228A1

公开(公告)日：2020-11-26

申请号：US16988508

申请日：2020-08-07

申请人： CalciMedica, Inc.

发明人： Gonul VELICELEBI ,  Kenneth STAUDERMAN ,  Michael DUNN ,  Jack ROOS

IPC分类号： A61K31/497 ,  A61K45/06 ,  A61K31/415 ,  A61K31/427 ,  A61K31/485 ,  C07D405/04 ,  C07D417/14 ,  A61K31/444 ,  A61K31/4155 ,  A61K31/506 ,  C07D401/04 ,  A61K31/421 ,  C07D417/10 ,  A61K31/4439 ,  C07D491/04 ,  C07D413/14 ,  A61P1/18

摘要： Compositions and methods related to the amelioration of pancreatitis through the pharmaceutical manipulation of calcium signaling are disclosed. Such compositions and methods may be used to ameliorate symptoms of acute or chronic pancreatitis or to reduce the chance or severity of pancreatitis in an individual at risk of the condition. In other embodiments, disclosed herein are compositions and methods related to the amelioration of viral diseases through the pharmaceutical manipulation of calcium signaling. In further embodiments, disclosed herein are compositions and methods related to the amelioration of Th17-induced diseases through the pharmaceutical manipulation of calcium signaling.