公开(公告)号：US09255120B2

公开(公告)日：2016-02-09

申请号：US14197511

申请日：2014-03-05

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Mark E. Davis ,  Rajamani Gounder

IPC: C07B37/08 ,  C07H3/02 ,  C07D307/62

CPC classification number: C07H3/02 ,  C07D307/62

Abstract: The present invention is directed to methods for preparing sorbose from glucose, said method comprising: (a) contacting the glucose with a silica-containing structure comprising a zeolite having a topology of a 12 membered-ring or larger, an ordered mesoporous silica material, or an amorphous silica, said structure containing Lewis acidic Ti4+ or Zr4+ or both Ti4+ and Zr4+ framework centers, said contacting conducted under reaction conditions sufficient to isomerize the glucose to sorbose. The sorbose may be (b) separated or isolated; or (c) converted to ascorbic acid.

Abstract translation: 本发明涉及从葡萄糖制备山梨糖的方法，所述方法包括：（a）使葡萄糖与包含具有12元环以上拓扑的沸石的二氧化硅结构物接触，有序介孔二氧化硅材料， 或无定形二氧化硅，所述结构含有Lewis酸性Ti4 +或Zr4 +或Ti4 +和Zr4 +骨架中心，所述接触在足以使葡萄糖异构化为山梨糖的反应条件下进行。 山梨糖可以是（b）分离或分离; 或（c）转化为抗坏血酸。