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342 条记录 (耗时 0.038 秒)

    Ethylenically unsaturated oligomers
    2.
    发明授权
    Ethylenically unsaturated oligomers 有权
    烯键式不饱和低聚物

    公开(公告)号：US09394244B2

    公开(公告)日：2016-07-19

    申请号：US14430934

    申请日：2013-10-22

    申请人： BASF SE

    发明人： Eugene Valentine Sitzmann ,  David Trumbo ,  Mervin Wood

    IPC分类号： C08F2/50 ,  C08F2/46 ,  C08G61/04 ,  C07C275/60 ,  C07D401/14 ,  C07C273/18 ,  C07D211/94 ,  C07D251/24 ,  C08F222/22 ,  C09D135/02 ,  C07D249/20 ,  C07D307/62

    CPC分类号： C07C275/60 ,  C07C273/1854 ,  C07D211/94 ,  C07D249/20 ,  C07D251/24 ,  C07D307/62 ,  C07D401/14 ,  C08F222/22 ,  C08G18/282 ,  C08G18/2825 ,  C08G18/73 ,  C08G18/755 ,  C08G18/7837 ,  C08G18/8166 ,  C09D135/02

    摘要： Disclosed are functional polyallophanate oligomers comprising ethylenically unsaturated groups and polymer stabilizer groups selected from hindered amine light stabilizers, ultraviolet light absorbers, antioxidants and dihydrocarbylhydroxylamines. The ethylenically unsaturated groups and the polymer stabilizer groups are bound to the polyallophanate oligomers through allophanate and/or carbamate groups. The polyallophanate oligomers are useful in curable coatings, inks and varnishes. The present polyallophanate oligomers are derived from a) organic polyisocyanates, b) compounds containing at least one isocyanate reactive group and at least one ethylenically unsaturated group and c) polymer stabilizers containing at least one isocyanate reactive group.

    摘要翻译： 公开了包含烯键式不饱和基团和选自受阻胺光稳定剂，紫外光吸收剂，抗氧化剂和二烃基羟胺的聚合物稳定剂基团的官能化聚山梨酸酯低聚物。 烯属不饱和基团和聚合物稳定剂基团通过脲基甲酸酯和/或氨基甲酸酯基团结合到多聚叶酸酯低聚物。 聚对苯二甲酸乙二醇酯低聚物可用于可固化涂料，油墨和清漆。 本发明的聚阴离子低聚物衍生自a）有机多异氰酸酯，b）含有至少一个异氰酸酯反应性基团和至少一个烯键式不饱和基团的化合物，和c）含有至少一个异氰酸酯反应性基团的聚合物稳定剂。

    Conversion of glucose to sorbose
    3.
    发明授权
    Conversion of glucose to sorbose 有权
    葡萄糖转化为山梨糖

    公开(公告)号：US09255120B2

    公开(公告)日：2016-02-09

    申请号：US14197511

    申请日：2014-03-05

    申请人： CALIFORNIA INSTITUTE OF TECHNOLOGY

    发明人： Mark E. Davis ,  Rajamani Gounder

    IPC分类号： C07B37/08 ,  C07H3/02 ,  C07D307/62

    CPC分类号： C07H3/02 ,  C07D307/62

    摘要： The present invention is directed to methods for preparing sorbose from glucose, said method comprising: (a) contacting the glucose with a silica-containing structure comprising a zeolite having a topology of a 12 membered-ring or larger, an ordered mesoporous silica material, or an amorphous silica, said structure containing Lewis acidic Ti4+ or Zr4+ or both Ti4+ and Zr4+ framework centers, said contacting conducted under reaction conditions sufficient to isomerize the glucose to sorbose. The sorbose may be (b) separated or isolated; or (c) converted to ascorbic acid.

    摘要翻译： 本发明涉及从葡萄糖制备山梨糖的方法，所述方法包括：（a）使葡萄糖与包含具有12元环以上拓扑的沸石的二氧化硅结构物接触，有序介孔二氧化硅材料， 或无定形二氧化硅，所述结构含有Lewis酸性Ti4 +或Zr4 +或Ti4 +和Zr4 +骨架中心，所述接触在足以使葡萄糖异构化为山梨糖的反应条件下进行。 山梨糖可以是（b）分离或分离; 或（c）转化为抗坏血酸。

    Dye-ascorbic acid derivatives
    6.
    发明授权
    Dye-ascorbic acid derivatives 失效
    染料 - 抗坏血酸衍生物

    公开(公告)号：US08709104B2

    公开(公告)日：2014-04-29

    申请号：US13812869

    申请日：2011-08-05

    申请人： Thomas Rudolph ,  Philipp Buehle

    发明人： Thomas Rudolph ,  Philipp Buehle

    IPC分类号： D06P1/02 ,  C09B37/00

    CPC分类号： C09B43/30 ,  A61K8/40 ,  A61K8/4946 ,  A61K8/4973 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q5/06 ,  A61Q5/065 ,  A61Q17/04 ,  C07D307/62 ,  C07D405/12 ,  C09B67/0051

    摘要： The invention relates to specific dye-ascorbic acid derivatives and the use thereof as dyes for the coloring of matrices, such as, for example, skin, hair, nails or textiles, and a process for the preparation thereof, a process for the coloring of matrices, and a composition comprising these dye-ascorbic acid derivatives, and a process for the preparation of these compositions. On use of the specific dye-ascorbic acid derivatives according to the invention, a positive effect on the moisture content of the matrices arises.

    摘要翻译： 本发明涉及特定的染料 - 抗坏血酸衍生物及其作为用于着色基质例如皮肤，毛发，指甲或纺织品的染料的用途及其制备方法，着色方法 基质和包含这些染料 - 抗坏血酸衍生物的组合物，以及制备这些组合物的方法。 在使用根据本发明的特定染料 - 抗坏血酸衍生物时，会产生对基质含水量的积极影响。

    Anti-human urothelial carcinoma of supercritical carbon dioxide extract of Cinnamomum subavenium, and the preparation process and uses
    7.
    发明授权
    Anti-human urothelial carcinoma of supercritical carbon dioxide extract of Cinnamomum subavenium, and the preparation process and uses 有权
    樟脑超临界二氧化碳提取物抗人尿路上皮癌及其制备方法和用途

    公开(公告)号：US08669377B2

    公开(公告)日：2014-03-11

    申请号：US13426136

    申请日：2012-03-21

    申请人： Jih-Heng Li ,  A-Mei Huang ,  Chung-Yi Chen ,  Pei-Jung Lien ,  Chiung-Hui Liu

    发明人： Jih-Heng Li ,  A-Mei Huang ,  Chung-Yi Chen ,  Pei-Jung Lien ,  Chiung-Hui Liu

    IPC分类号： C07D307/02

    CPC分类号： A61K33/24 ,  A61K31/085 ,  A61K31/365 ,  A61K31/515 ,  A61K31/555 ,  A61K31/7068 ,  A61K36/54 ,  A61K2236/00 ,  C07D307/62 ,  Y02P20/544 ,  A61K2300/00

    摘要： What is disclosed in the invention is a preparation method of a supercritical Cinnamomum subavenium extract, which is made from the material, the dried stem of C. subavenium. The extract is obtained by extracting C. subavenium which is pulverized as particles with supercritical carbon dioxide fluid. The C. subavenium extract or its active ingredient, subamolide A, can be used to inhibit the growth of human urothelial carcinoma cell lines. In addition, the C. subavenium extract (or subamolide A) is able to synergistically inhibit the growth of human urothelial carcinoma cell lines with cisplatin (CDDP) or gemcitabine (Gem). Therefore, the C. subavenium extract (or subamolide A) can be an anticancer drug alone, or forms a pharmaceutical composition with CDDP (or Gem) to treat with cancers in respect of urinary system.

    摘要翻译： 本发明公开的是超临界樟脑提取物的制备方法，该方法由材料，sub the的干茎制成。 提取物是通过提取用超临界二氧化碳流体粉碎成颗粒的sub壳来获得的。 sub ium提取物或其活性成分，亚胺酸A可用于抑制人尿路上皮癌细胞系的生长。 另外，唾液天竺葵提取物（或亚单位面积A）能够协同地抑制人顺铂（GDP）或吉西他滨（Gem）的人尿路上皮癌细胞株的生长。 因此，sub ium ium ium extract extract（））））））））））））。。。。。。。。。。。。。。。。。。。。。。。。。。。。

    Aryl (Ethanoic) Propanoic Acid Ascorbyl Ester, Preparation Method Thereof And Medicament Containing The Same
    10.
    发明申请
    Aryl (Ethanoic) Propanoic Acid Ascorbyl Ester, Preparation Method Thereof And Medicament Containing The Same 有权
    （乙酸）丙酸抗坏血酸酯，其制备方法和含有其的药物

    公开(公告)号：US20120115897A1

    公开(公告)日：2012-05-10

    申请号：US13320101

    申请日：2009-12-24

    申请人： Luhong Tang ,  Ajuan Dai ,  Ze Wang ,  Yang Sun ,  Xinning Liu ,  Lingyan Xu ,  Xin Fang ,  Shuang Qiu ,  Yaqing Cao ,  Xiaomin Xu ,  Ruixia Jiang ,  Chao Wu

    发明人： Luhong Tang ,  Ajuan Dai ,  Ze Wang ,  Yang Sun ,  Xinning Liu ,  Lingyan Xu ,  Xin Fang ,  Shuang Qiu ,  Yaqing Cao ,  Xiaomin Xu ,  Ruixia Jiang ,  Chao Wu

    IPC分类号： A61K31/436 ,  C07D491/052 ,  C12P17/04 ,  C12P17/18 ,  A61K31/375 ,  A61K31/407 ,  A61P29/00 ,  A61P19/02 ,  A61P25/00 ,  A61P25/28 ,  A61P35/00 ,  A61P15/00 ,  A61P11/00 ,  A61P9/00 ,  C07D307/62

    CPC分类号： C07D307/62 ,  C07D405/12 ,  C07D491/04 ,  C07D491/052 ,  C12P17/04 ,  C12P17/16 ,  C12P17/188 ,  C12Y301/01003

    摘要： The present invention designs and synthesizes the ascorbyl ester derivatives of the aryl (ethanoic) propanoic acid non-steroidal anti-inflammatory medicaments, such as ibuprofen, ketoprofen and naproxen, and addition salt of the derivatives with pharmaceutical acid or pharmaceutical alkaline. The non-steroidal anti-inflammatory medicament which takes the ibuprofen as the representative is a common antipyretic analgesic medicament. The invention has remarkable antipyretic and analgesic effects and good safety except for anti-inflammatory effect, thus being not only suitable for adults, but also suitable for the elderly people, infants and children. The aryl (ethanoic) propanoic acid ascorbyl ester can be converted into ascorbyl ester derivatives and the addition salts of the derivatives with pharmaceutical acid or pharmaceutical alkaline, which can improve the water solubility thereof, facilitate intravenously administration, reduce the onset time, improve the bioavailability, reduce the stimulation effect to gastrointestinal tract, and enhance the penetrating capacity to hemato encephalic barrier, and can be used as a novel medicament to be applied for antiphlogistic, antipyresis, analgesia, treatment of arthritis, dysmenorrheal, multiple sclerosis, pneumonia cystic fibrosis and patent ductus arteriosus of premature infants, and prevention and treatment of cerebral apoplexy, hypoxic-ischemic brain damage, senile dementia and certain cancers.

    摘要翻译： 本发明设计和合成芳基（乙酸）丙酸非甾体抗炎药物如布洛芬，酮洛芬和萘普生的抗坏血酸酯衍生物，以及衍生物与药物酸或药物碱的加成盐。 以布洛芬为代表的非甾体抗炎药是常见的解热止痛药。 本发明除抗炎作用外，具有明显的解热镇痛作用，安全性好，不仅适用于成人，而且适用于老年人，婴儿和儿童。 芳基（乙酸）丙酸抗坏血酸酯可以转化为抗坏血酸酯衍生物，并且衍生物的加成盐与药物酸或药物碱性可以改善其水溶性，有助于静脉内施用，减少发病时间，提高生物利用度 降低对胃肠道的刺激作用，增强血液渗透屏障的穿透能力，可用作新型药物，用于消炎止痛，止痛，止痛，治疗关节炎，痛经，多发性硬化，肺炎囊性纤维化，以及 早产儿动脉导管未闭，预防和治疗脑中风，缺氧缺血性脑损伤，老年性痴呆和某些癌症。