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公开(公告)号:US11426420B2
公开(公告)日:2022-08-30
申请号:US16603544
申请日:2018-04-09
发明人: Sanford Markowitz , Won Jin Ho , Yiyuan Yuan , Mukesh Jain , Mohamed Sabeh , Joseph Ready , Noelle Williams
IPC分类号: A61K31/704 , A61P9/00 , A61K31/4355 , A61K31/4365 , A61K31/437 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/7048 , C07K16/32
摘要: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
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公开(公告)号:US20230165883A1
公开(公告)日:2023-06-01
申请号:US17893777
申请日:2022-08-23
发明人: Sanford Markowitz , Won Jin Ho , Yiyuan Yuan , Mukesh Jain , Mohamad Sabeh , Joseph Ready , Noelle Williams
IPC分类号: A61K31/704 , A61P9/00 , A61K31/4355 , A61K31/4365 , A61K31/437 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/7048 , C07K16/32
CPC分类号: A61K31/704 , A61P9/00 , A61K31/4355 , A61K31/4365 , A61K31/437 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/7048 , C07K16/32
摘要: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
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公开(公告)号:US20200030348A1
公开(公告)日:2020-01-30
申请号:US16603544
申请日:2018-04-09
发明人: Sanford Markowitz , Won Jin Ho , Yiyuan Yuan , Mukesh Jain , Mohamed Sabeh , Joseph Ready , Noelle Williams
IPC分类号: A61K31/704 , A61K31/7048 , A61K31/4365 , C07K16/32 , A61K31/519 , A61K31/437 , A61K31/4355 , A61K31/5377 , A61K31/496 , A61P9/00
摘要: A method of treating preventing, minimizing, and/or reversing congestive heart failure, cardiomyopathy, and/or reduction of cardiac ejection fraction in a subject in need thereof includes administering to the subject a therapeutically effective amount of a 15-PGDH inhibitor.
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