公开(公告)号：US20240285792A1

公开(公告)日：2024-08-29

申请号：US18426706

申请日：2024-01-30

申请人： CASE WESTERN RESERVE UNIVERSITY ,  MASSACHUSETTS INSTITUTE OF TECHNOLOGY

发明人： Nicole F. Steinmetz ,  Stephen Lippard ,  Anna Czapar ,  Yaorong Zheng

IPC分类号： A61K47/69 ,  A61K9/00 ,  A61K9/51 ,  A61K31/555 ,  A61K39/00 ,  A61K39/12 ,  A61P35/00

CPC分类号： A61K47/6901 ,  A61K9/0019 ,  A61K9/5184 ,  A61K31/555 ,  A61K39/12 ,  A61P35/00 ,  A61K2039/585 ,  C12N2750/12022 ,  C12N2750/12023 ,  C12N2770/00034 ,  C12N2770/00042 ,  C12N2770/32022 ,  C12N2770/32023

摘要： Anticancer virus particles are described. Anticancer virus particles are filamentous or rod-shaped plant virus particle containing an anticancer agent within the interior of the virus particle. The anticancer agent can be attached either covalently or non-covalently within the interior of the virus particle. A therapeutically effective amount of an anticancer virus particle can be administered to a subject identified as having cancer to provide a method of cancer treatment.

公开(公告)号：US11883505B2

公开(公告)日：2024-01-30

申请号：US16854444

申请日：2020-04-21

申请人： CASE WESTERN RESERVE UNIVERSITY ,  MASSACHUSETTS INSTITUTE OF TECHNOLOGY

发明人： Nicole F. Steinmetz ,  Stephen J. Lippard ,  Anna Czapar ,  Yaorong Zheng

IPC分类号： A61P35/00 ,  A61K9/19 ,  A61K31/555 ,  A61K39/12 ,  A61K47/69 ,  A61K9/00 ,  A61K9/51 ,  A61K39/00

CPC分类号： A61K47/6901 ,  A61K9/0019 ,  A61K9/5184 ,  A61K31/555 ,  A61K39/12 ,  A61P35/00 ,  A61K2039/585 ,  C12N2750/12022 ,  C12N2750/12023 ,  C12N2770/00034 ,  C12N2770/00042 ,  C12N2770/32022 ,  C12N2770/32023

摘要： Anticancer virus particles are described. Anticancer virus particles are filamentous or rod-shaped plant virus particle containing an anticancer agent within the interior of the virus particle. The anticancer agent can be attached either covalently or non-covalently within the interior of the virus particle. A therapeutically effective amount of an anticancer virus particle can be administered to a subject identified as having cancer to provide a method of cancer treatment.

公开(公告)号：US20200246482A1

公开(公告)日：2020-08-06

申请号：US16854444

申请日：2020-04-21

申请人： CASE WESTERN RESERVE UNIVERSITY ,  MASSACHUSETTS INSTITUTE OF TECHNOLOGY

发明人： Nicole F. Steinmetz ,  Stephen J. Lippard ,  Anna Czapar ,  Yaorong Zheng

IPC分类号： A61K47/69 ,  A61P35/00 ,  A61K9/51 ,  A61K9/00 ,  A61K31/555 ,  A61K39/12

摘要： Anticancer virus particles are described. Anticancer virus particles are filamentous or rod-shaped plant virus particle containing an anticancer agent within the interior of the virus particle. The anticancer agent can be attached either covalently or non-covalently within the interior of the virus particle. A therapeutically effective amount of an anticancer virus particle can be administered to a subject identified as having cancer to provide a method of cancer treatment.