"> USE OF RECOMBINANT TYPE III
    2.
    发明申请
    USE OF RECOMBINANT TYPE III "POLYKETIDE SYNTHASES" (PKS III) OF MARINE BROWN ALGAE 审中-公开
    重型III型“聚合酶合成酶”(PKS III)的应用

    公开(公告)号:US20140315269A1

    公开(公告)日:2014-10-23

    申请号:US14348490

    申请日:2012-09-26

    IPC分类号: C12P7/22 C12N9/00

    摘要: The present invention relates to a method for producing polyphenol compounds, i.e. phloroglucinol or one of its derivatives, with a polyketide synthase of type III (PKSIII) from a brown marine alga. The invention also relates to recombinant nucleic acids coding for a polyketide synthase of type III (PKSIII) from the brown alga Ectocarpus siliculosus (E. siliculosus), to recombinant vectors comprising these nucleic acids, as well as to host cells comprising these vectors. Finally, the invention relates to a method for preparing of various compounds by means of polyphenol compounds produced according to the aforementioned method.

    摘要翻译: 本发明涉及一种多酚化合物,即间苯三酚或其衍生物之一与来自棕色海洋藻类的III型(PKSIII)聚酮化合物合成酶的方法。 本发明还涉及编码来自褐藻(E.silulosus)的III型(PKSIII)的聚酮化合物合酶,包含这些核酸的重组载体以及包含这些载体的宿主细胞的重组核酸。 最后,本发明涉及通过根据上述方法生产的多酚化合物制备各种化合物的方法。