公开(公告)号：US20220409615A1

公开(公告)日：2022-12-29

申请号：US17318693

申请日：2021-05-12

Applicant: CHDI Foundation, Inc.

Inventor： Celia Dominguez ,  Elizabeth M. Doherty ,  Longbin Liu ,  Matthew Lee ,  Mark Stuart Chambers ,  Karine Fabienne Malagu ,  Perla Breccia ,  Alan F. Haughan ,  Huw D. Vater ,  Andrew J. Stott ,  William R. K. Esmieu ,  Stephen John Webster ,  Amanda J. Van De Poël

IPC: A61K31/497 ,  C07D471/04 ,  C07D519/00 ,  A61K31/4985 ,  C07D487/04 ,  C07D403/14 ,  A61K31/506 ,  A61K31/501 ,  C07D413/14 ,  A61P25/28

Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.

公开(公告)号：US11806346B2

公开(公告)日：2023-11-07

申请号：US17318693

申请日：2021-05-12

Applicant: CHDI Foundation, Inc.

Inventor： Celia Dominguez ,  Elizabeth M. Doherty ,  Longbin Liu ,  Matthew Lee ,  Mark Stuart Chambers ,  Karine Fabienne Malagu ,  Perla Breccia ,  Alan F. Haughan ,  Huw D. Vater ,  Andrew J. Stott ,  William R. K. Esmieu ,  Stephen John Webster ,  Amanda J. Van De Poël

IPC: A61K31/497 ,  A61P25/28 ,  A61K31/4985 ,  A61K31/501 ,  A61K31/506 ,  C07D403/14 ,  C07D413/14 ,  C07D471/04 ,  C07D487/04 ,  C07D519/00

CPC classification number: A61K31/497 ,  A61K31/4985 ,  A61K31/501 ,  A61K31/506 ,  A61P25/28 ,  C07D403/14 ,  C07D413/14 ,  C07D471/04 ,  C07D487/04 ,  C07D519/00

Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.