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公开(公告)号:US20210236663A1
公开(公告)日:2021-08-05
申请号:US17125905
申请日:2020-12-17
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Christopher John Brown , Sarah Hayes , Adrian Kotey , Matthew Robert Mills , Michael Edward Prime
IPC: A61K51/04 , C07D401/14 , C07D401/06 , C07D471/04 , C07D401/12 , C07D491/107 , C07D487/04 , C07D413/14 , C07B59/00
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US20240342317A1
公开(公告)日:2024-10-17
申请号:US18402399
申请日:2024-01-02
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC: A61K51/04 , C07B59/00 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00
CPC classification number: A61K51/0459 , A61K51/0455 , A61K51/0463 , C07B59/002 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00 , C07B2200/05
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US11918662B2
公开(公告)日:2024-03-05
申请号:US17344582
申请日:2021-06-10
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC: A61K51/04 , C07B59/00 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00
CPC classification number: A61K51/0459 , A61K51/0455 , A61K51/0463 , C07B59/002 , C07D231/12 , C07D471/04 , C07D487/04 , C07D487/14 , C07D519/00 , C07B2200/05
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US20210393812A1
公开(公告)日:2021-12-23
申请号:US17344582
申请日:2021-06-10
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Catherine Jane Greenaway , Kanika Khurana , Matthew Robert Mills , Filippo Rota
IPC: A61K51/04 , C07B59/00 , C07D487/04 , C07D487/14 , C07D519/00 , C07D231/12 , C07D471/04
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US11806346B2
公开(公告)日:2023-11-07
申请号:US17318693
申请日:2021-05-12
Applicant: CHDI Foundation, Inc.
Inventor: Celia Dominguez , Elizabeth M. Doherty , Longbin Liu , Matthew Lee , Mark Stuart Chambers , Karine Fabienne Malagu , Perla Breccia , Alan F. Haughan , Huw D. Vater , Andrew J. Stott , William R. K. Esmieu , Stephen John Webster , Amanda J. Van De Poël
IPC: A61K31/497 , A61P25/28 , A61K31/4985 , A61K31/501 , A61K31/506 , C07D403/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D519/00
CPC classification number: A61K31/497 , A61K31/4985 , A61K31/501 , A61K31/506 , A61P25/28 , C07D403/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D519/00
Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.
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公开(公告)号:US11992535B2
公开(公告)日:2024-05-28
申请号:US17125905
申请日:2020-12-17
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Matthew Lee , Celia Dominguez , Peter David Johnson , Christopher John Brown , Sarah Hayes , Adrian Kotey , Matthew Robert Mills , Michael Edward Prime
IPC: A61K51/04 , C07B59/00 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D491/107
CPC classification number: A61K51/0455 , A61K51/0459 , A61K51/0468 , C07B59/00 , C07D401/06 , C07D401/12 , C07D401/14 , C07D413/14 , C07D471/04 , C07D487/04 , C07D491/107 , C07B2200/05
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a condition or disorder associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US20220409615A1
公开(公告)日:2022-12-29
申请号:US17318693
申请日:2021-05-12
Applicant: CHDI Foundation, Inc.
Inventor: Celia Dominguez , Elizabeth M. Doherty , Longbin Liu , Matthew Lee , Mark Stuart Chambers , Karine Fabienne Malagu , Perla Breccia , Alan F. Haughan , Huw D. Vater , Andrew J. Stott , William R. K. Esmieu , Stephen John Webster , Amanda J. Van De Poël
IPC: A61K31/497 , C07D471/04 , C07D519/00 , A61K31/4985 , C07D487/04 , C07D403/14 , A61K31/506 , A61K31/501 , C07D413/14 , A61P25/28
Abstract: Provided herein are certain compounds useful as HTT modulators. Such compound are useful in the treatment of Huntington's disease.
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