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公开(公告)号:US20220372045A1
公开(公告)日:2022-11-24
申请号:US17729881
申请日:2022-04-26
Applicant: CHDI Foundation, Inc.
Inventor: Longbin Liu , Celia Dominguez , Jonathan Bard , Vinod Khetarpal , Ashley Jarvis , Sarah Hayes , John E. Mangette
IPC: C07D498/04 , A61K51/04
Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
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公开(公告)号:US11173156B2
公开(公告)日:2021-11-16
申请号:US16898239
申请日:2020-06-10
Applicant: CHDI Foundation, Inc.
Inventor: Leticia M. Toledo-Sherman , Celia Dominguez , Vinod Khetarpal , Travis Lee Houston , Stephan D. Parent , Jian-xie Chen , Charles H. Montgomery , Geetha Banda
IPC: A61K31/505 , C07D239/28
Abstract: Forms of 6-(3-chloro-4-cyclopropoxyphenyl)pyrimidine-4-carboxylic acid (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the forms of Compound I and salts or co-crystals thereof.
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