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公开(公告)号：US20160207957A1
公开(公告)日：2016-07-21
申请号：US14914374
申请日：2014-08-28
IPC分类号： C07K1/107 , C07C269/04 , C07C269/06 , C07C323/60 , C07K14/62 , C08F112/14 , C07K14/605 , C07K14/505 , C07K14/575 , C07K14/635 , C07K14/47 , C07K14/00 , C07C271/02 , A61K47/48
CPC分类号： C07K1/1075 , A61K38/00 , A61K47/542 , C07C269/04 , C07C269/06 , C07C271/02 , C07C323/60 , C07C2603/18 , C07K1/04 , C07K1/1077 , C07K14/00 , C07K14/4703 , C07K14/473 , C07K14/505 , C07K14/575 , C07K14/57509 , C07K14/605 , C07K14/62 , C07K14/635 , C07K14/695 , C08F112/14
摘要： The present invention relates to peptide modifier compounds of Formula (1), or a salt thereof, wherein: a is an integer from 1 to 10, more preferably from 1 to 3; b is an integer from 0 to 7; Z is a terminal group and Y is a bivalent group. Further aspects of the invention relate to intermediates in the preparation of compounds of Formula (1), and the use of compounds of Formula 1 in the synthesis of peptide derivatives.
摘要翻译： 本发明涉及式（1）的肽改性剂化合物或其盐，其中：a为1至10的整数，更优选为1至3; b为0〜7的整数; Z是末端基团，Y是二价基团。 本发明的其它方面涉及制备式（1）化合物的中间体，以及式1的化合物在肽衍生物的合成中的用途。
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公开(公告)号：US20190177362A1
公开(公告)日：2019-06-13
申请号：US16195145
申请日：2018-11-19
IPC分类号： C07K1/107 , C07K14/575 , C07K14/62 , C07K14/00 , C07C269/06 , C07C271/02 , C07C323/60 , C08F112/14 , C07K14/47 , A61K47/54 , C07C269/04 , C07K14/605 , C07K1/04 , C07K14/695 , C07K14/635 , C07K14/505
摘要： The present invention relates to peptide modifier compounds of Formula (1), or a salt thereof, wherein: a is an integer from 1 to 10, more preferably from 1 to 3; b is an integer from 0 to 7; Z is a terminal group and Y is a bivalent group. Further aspects of the invention relate to intermediates in the preparation of compounds of Formula (1), and the use of compounds of Formula 1 in the synthesis of peptide derivatives.
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公开(公告)号：US20240002433A1
公开(公告)日：2024-01-04
申请号：US18189057
申请日：2023-03-23
IPC分类号： C07K1/107 , C07K14/505 , C07K14/575 , C07K14/62 , C07K14/635 , C07K14/695 , C07K1/04 , C07K14/605 , A61K47/54 , C07C269/04 , C07C269/06 , C07C271/02 , C07C323/60 , C07K14/00 , C07K14/47
CPC分类号： C07K1/1075 , C07K14/505 , C07K14/57509 , C07K14/62 , C07K14/635 , C07K14/695 , C07K1/04 , C07K1/1077 , C07K14/575 , C07K14/605 , A61K47/542 , C07C269/04 , C07C269/06 , C07C271/02 , C07C323/60 , C07K14/00 , C07K14/4703 , C07K14/473 , C07C2603/18 , A61K38/00
摘要： The present invention relates to peptide modifier compounds of Formula (1), or a salt thereof, wherein: a is an integer from 1 to 10, more preferably from 1 to 3; b is an integer from 0 to 7; Z is a terminal group and Y is a bivalent group. Further aspects of the invention relate to intermediates in the preparation of compounds of Formula (1), and the use of compounds of Formula (1) in the synthesis of peptide derivatives.
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公开(公告)号：US11634455B2
公开(公告)日：2023-04-25
申请号：US16195145
申请日：2018-11-19
IPC分类号： C07K14/505 , C07K1/107 , C07K14/575 , C07K14/62 , C07K14/635 , C07K14/695 , C07K1/04 , C07K14/605 , A61K47/54 , C07C269/04 , C07C269/06 , C07C271/02 , C07C323/60 , C07K14/00 , C07K14/47 , A61K38/00
摘要： The present invention relates to peptide modifier compounds of Formula (1), or a salt thereof, wherein: a is an integer from 1 to 10, more preferably from 1 to 3; b is an integer from 0 to 7; Z is a terminal group and Y is a bivalent group. Further aspects of the invention relate to intermediates in the preparation of compounds of Formula (1), and the use of compounds of Formula 1 in the synthesis of peptide derivatives.
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