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公开(公告)号：US09745308B2
公开(公告)日：2017-08-29
申请号：US14840420
申请日：2015-08-31
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Matteo Biagetti , Anna Maria Capelli , Matilde Guala
IPC: C07D473/34 , C07D403/12 , A61K31/5377 , A61K31/52 , A61K31/519 , A61K31/506 , C07D487/04
CPC classification number: C07D487/04 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/5377 , C07D403/12 , C07D473/34 , Y02A50/409
Abstract: Compounds of formula (I) described herein inhibit phosphoinositide 3-kinases (PI3K) and useful for the treatment of disorders associated with PI3K enzymes.
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Patent Agency Ranking
公开(公告)号：US09527869B2
公开(公告)日：2016-12-27
申请号：US14741965
申请日：2015-06-17
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Matteo Biagetti , Alessandro Accetta , Anna Maria Capelli , Matilde Guala , Michele Retini
IPC: C07D487/04 , C07D471/04 , C07D473/02 , C07D519/00 , A61K31/519 , A61K31/5377 , A61K31/53 , A61K31/52 , A61K31/506 , A61K31/497 , A61P19/02 , A61P11/00 , A61P11/02
CPC classification number: C07D519/00 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/5377 , C07D471/04 , C07D473/02 , C07D487/04 , Y02A50/409
Abstract: Compounds of formula (I), defined herein, inhibit phosphoinositide 3-kinases (PI3K) and are useful for the treatment of disorders associated with PI3K enzymes.
Abstract translation: 本文定义的式（I）化合物抑制磷酸肌醇3-激酶（PI3K），可用于治疗与PI3K酶相关的疾病。
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公开(公告)号：US10189844B2
公开(公告)日：2019-01-29
申请号：US15420513
申请日：2017-01-31
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Matteo Biagetti , Anna Maria Capelli , Michele Retini
IPC: C07D487/04 , A61K31/519 , A61K45/06
Abstract: Compounds of formula (I) defined herein are phosphoinositide 3-kinases (PI3K) inhibitors and are useful for the treatment of disorders associated with PI3K enzymes.
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公开(公告)号：US09968604B2
公开(公告)日：2018-05-15
申请号：US15079740
申请日：2016-03-24
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Anna Maria Capelli , Matteo Biagetti , Alessandro Accetta
IPC: A61K31/519 , A61K31/52 , C07D403/12 , C07D405/12 , C07D473/34 , C07D487/04 , A61K31/506
CPC classification number: A61K31/506 , A61K31/519 , A61K31/52 , C07D403/12 , C07D405/12 , C07D473/34 , C07D487/04
Abstract: Chromene compounds of formula (I), defined herein, inhibit phosphoinositide 3-kinases (PI3K) and are useful for the treatment of disorders associated with a PI3K enzyme mechanism, such as asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis.
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公开(公告)号：US09321776B2
公开(公告)日：2016-04-26
申请号：US14573887
申请日：2014-12-17
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Matteo Biagetti , Anna Maria Capelli , Alessandro Accetta , Laura Carzaniga
IPC: C07D487/04 , C07D473/38 , C07D471/04 , C07D495/04 , C07D413/14 , C07D519/00 , C07D473/34 , C07D405/12 , A61K31/52 , A61K45/06 , A61K31/506 , A61K31/519 , A61K31/53 , A61K31/5377 , C07D417/04 , C07D473/16
CPC classification number: C07D487/04 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/53 , A61K31/5377 , A61K45/06 , C07D405/12 , C07D413/14 , C07D417/04 , C07D471/04 , C07D473/16 , C07D473/34 , C07D473/38 , C07D495/04 , C07D519/00 , Y02A50/409 , A61K2300/00
Abstract: Compounds of formula (I) described herein are useful for inhibiting phosphoinositide 3-kinases (PI3K) and the treatment of disorders associated with PI3K enzymes.
Abstract translation: 本文所述的式（I）化合物可用于抑制磷酸肌醇3-激酶（PI3K）和治疗与PI3K酶相关的病症。
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公开(公告)号：US20150166549A1
公开(公告)日：2015-06-18
申请号：US14573887
申请日：2014-12-17
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Matteo Biagetti , Anna Maria Capelli , Alessandro Accetta , Laura Carzaniga
IPC: C07D487/04 , C07D473/38 , C07D471/04 , C07D473/16 , C07D495/04 , C07D413/14 , C07D519/00 , C07D473/34 , C07D405/12
CPC classification number: C07D487/04 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/53 , A61K31/5377 , A61K45/06 , C07D405/12 , C07D413/14 , C07D417/04 , C07D471/04 , C07D473/16 , C07D473/34 , C07D473/38 , C07D495/04 , C07D519/00 , Y02A50/409 , A61K2300/00
Abstract: Compounds of formula (I) described herein are useful for inhibiting phosphoinositide 3-kinases (PI3K) and the treatment of disorders associated with PI3K enzymes.
Abstract translation: 本文所述的式（I）化合物可用于抑制磷酸肌醇3-激酶（PI3K）和治疗与PI3K酶相关的病症。
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