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Patent Agency Ranking
公开(公告)号：US09745308B2
公开(公告)日：2017-08-29
申请号：US14840420
申请日：2015-08-31
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Matteo Biagetti , Anna Maria Capelli , Matilde Guala
IPC: C07D473/34 , C07D403/12 , A61K31/5377 , A61K31/52 , A61K31/519 , A61K31/506 , C07D487/04
CPC classification number: C07D487/04 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/5377 , C07D403/12 , C07D473/34 , Y02A50/409
Abstract: Compounds of formula (I) described herein inhibit phosphoinositide 3-kinases (PI3K) and useful for the treatment of disorders associated with PI3K enzymes.
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2.发明申请DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS 有权1-苯基-2-吡啶基亚胺醇作为磷酸二酯酶抑制剂的衍生物公开(公告)号：US20130102576A1
公开(公告)日：2013-04-25
申请号：US13655903
申请日：2012-10-19
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： Elisabetta ARMANI , Gabriele Amari , Carmelida Capaldi , Laura Carzaniga , Elena La Porta , Matilde Guala
IPC: A61K31/4425 , C07D401/12 , A61K31/4439 , C07D473/06 , A61K31/522 , A61K31/498 , A61K31/502 , C07D413/14 , A61K31/5377 , C07D417/14 , A61K31/541 , A61K31/56 , A61P11/00 , A61P11/06 , A61P37/00 , A61P17/00 , A61M15/00 , A61M11/00 , A61M16/14 , C07D213/89
CPC classification number: C07D401/12 , C07D401/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D473/04
Abstract: Compounds, pyridine N-oxides, and pharmaceutically acceptable salts of formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and for preventing and/or treating diseases of the respiratory tract characterized by airway obstruction, such as asthma or COPD.
Abstract translation: 化合物，吡啶N-氧化物和式（I）的药学上可接受的盐可用作磷酸二酯酶4（PDE4）酶的抑制剂，并且用于预防和/或治疗以气道阻塞为特征的呼吸道疾病如哮喘或COPD 。
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公开(公告)号：US09527869B2
公开(公告)日：2016-12-27
申请号：US14741965
申请日：2015-06-17
Applicant: CHIESI FARMACEUTICI S.P.A.
Inventor： Matteo Biagetti , Alessandro Accetta , Anna Maria Capelli , Matilde Guala , Michele Retini
IPC: C07D487/04 , C07D471/04 , C07D473/02 , C07D519/00 , A61K31/519 , A61K31/5377 , A61K31/53 , A61K31/52 , A61K31/506 , A61K31/497 , A61P19/02 , A61P11/00 , A61P11/02
CPC classification number: C07D519/00 , A61K31/497 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/5377 , C07D471/04 , C07D473/02 , C07D487/04 , Y02A50/409
Abstract: Compounds of formula (I), defined herein, inhibit phosphoinositide 3-kinases (PI3K) and are useful for the treatment of disorders associated with PI3K enzymes.
Abstract translation: 本文定义的式（I）化合物抑制磷酸肌醇3-激酶（PI3K），可用于治疗与PI3K酶相关的疾病。
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公开(公告)号：US20160075710A1
公开(公告)日：2016-03-17
申请号：US14840420
申请日：2015-08-31
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： Matteo BIAGETTI , Anna Maria Capelli , Matilde Guala
IPC: C07D487/04 , A61K31/5377 , A61K31/52 , A61K31/506 , C07D473/34 , A61K31/519 , C07D403/12
CPC classification number: C07D487/04 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/5377 , C07D403/12 , C07D473/34 , Y02A50/409
Abstract: Compounds of formula (I) described herein inhibit phosphoinositide 3-kinases (PI3K) and useful for the treatment of disorders associated with PI3K enzymes.
Abstract translation: 本文所述的式（I）化合物抑制磷酸肌醇3-激酶（PI3K）并且可用于治疗与PI3K酶相关的病症。
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5.发明授权Derivatives of 1-phenyl-2-pyridinyl alkyl alcohols as phosphodiesterase inhibitors 有权1-苯基-2-吡啶基烷基醇的衍生物作为磷酸二酯酶抑制剂公开(公告)号：US09024027B2
公开(公告)日：2015-05-05
申请号：US13655903
申请日：2012-10-19
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： Elisabetta Armani , Gabriele Amari , Carmelida Capaldi , Laura Carzaniga , Elena La Porta , Matilde Guala
IPC: C07D413/14 , C07D413/12 , C07D409/14 , C07D401/14 , C07D401/12 , A61K31/44 , C07D417/12 , C07D417/14 , C07D471/04 , C07D473/04
CPC classification number: C07D401/12 , C07D401/14 , C07D409/14 , C07D413/12 , C07D413/14 , C07D417/12 , C07D417/14 , C07D471/04 , C07D473/04
Abstract: Compounds, pyridine N-oxides, and pharmaceutically acceptable salts of formula (I) are useful as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and for preventing and/or treating diseases of the respiratory tract characterized by airway obstruction, such as asthma or COPD.
Abstract translation: 化合物，吡啶N-氧化物和式（I）的药学上可接受的盐可用作磷酸二酯酶4（PDE4）酶的抑制剂，并且用于预防和/或治疗以气道阻塞为特征的呼吸道疾病如哮喘或COPD 。
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