公开(公告)号：US20180171370A1

公开(公告)日：2018-06-21

申请号：US15735096

申请日：2015-06-12

Applicant: CJ Cheiljedang Corporation

Inventor： Eun Bin YANG ,  Tae Hee LEE ,  Seon Hye KIM ,  Gyuhyeon SONG ,  Cheol Woong HA ,  Kyungsu NA ,  Young Lyeol YANG ,  Min Sun KANG ,  Hyo Hyoung LEE

IPC: C12P7/56 ,  C12N9/88 ,  C12N9/02 ,  C12N9/00 ,  C12N1/18

CPC classification number: C12P7/56 ,  C12N1/18 ,  C12N9/0008 ,  C12N9/88 ,  C12N9/93 ,  C12Y102/01003 ,  C12Y401/01001 ,  C12Y602/01001

Abstract: The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased activities of aldehyde dehydrogenase (ALD) and acetyl-CoA synthetase (ACS), and a method of producing lactic acid from the culture medium obtained by culturing the microorganism.

公开(公告)号：US20240368662A1

公开(公告)日：2024-11-07

申请号：US18568649

申请日：2022-06-07

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Yeong Eun IM ,  Cheol Woong HA ,  Eun Bin YANG ,  Yeonsoo KIM

IPC: C12P21/02 ,  C12N9/02

Abstract: The present application relates to a superoxide dismutase 1 variant and a method for producing glutathione or derivatives thereof using the same.

公开(公告)号：US20180320206A1

公开(公告)日：2018-11-08

申请号：US15735074

申请日：2016-06-10

Applicant: CJ Cheiljedang Corporation

Inventor： Seon Hye KIM ,  Tae Hee LEE ,  Young Lyeol YANG ,  Eun Bin YANG ,  Kyungsu NA ,  Cheol Woong HA

IPC: C12P7/56 ,  C07K14/395 ,  C12N15/81

CPC classification number: C12P7/56 ,  C07K14/395 ,  C12N15/81 ,  C12Y101/01002 ,  C12Y101/01028 ,  C12Y401/01001

Abstract: The present application relates to a microorganism of the genus Saccharomyces producing lactic acid and a method for preparing lactic acid using the same. More specifically, the present application relates to a microorganism of the genus Saccharomyces producing lactic acid, wherein the microorganism is modified to weaken or inactivate the activity of pyruvate decarboxylase (PDC) compared to its endogenous activity, to introduce the activity of ATP-citrate lyase (ACL), and to enhance pyruvate biosynthetic pathway compared to its endogenous biosynthetic pathway, and a method for producing lactic acid using the microorganism.

公开(公告)号：US20170175150A1

公开(公告)日：2017-06-22

申请号：US14783012

申请日：2015-05-08

Applicant: CJ CHEILJEDANG CORPORATION

Inventor： Eun Bin YANG ,  Tae Hee LEE ,  Seon Hye KIM ,  Gyu Hyeon SONG ,  Cheol Woong HA ,  Kyung Su NA ,  Young Lyeol YANG ,  Min Sun KANG ,  Hyo Hyoung LEE

IPC: C12P7/56 ,  C12N9/02 ,  C12N9/00 ,  C12N9/04 ,  C12N9/88

CPC classification number: C12P7/56 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/88 ,  C12N9/93 ,  C12Y101/01027 ,  C12Y101/01028 ,  C12Y401/01001 ,  C12Y602/01001

Abstract: The present invention relates to Saccharomyces sp. capable of producing lactic acid with a decreased activity of pyruvate decarboxylase (PDC) and increased activities of aldehyde dehydrogenase (ALD) and acetyl-CoA synthetase (ACS), and a method of producing lactic acid from the culture medium obtained by culturing the microorganism.