公开(公告)号：US09687482B2

公开(公告)日：2017-06-27

申请号：US14608560

申请日：2015-01-29

申请人： CJ HEALTHCARE CORPORATION

发明人： Young Hee Suh ,  Young Dae Cho ,  Chun Seon Lyu ,  Mi Young Yoon ,  Ha Yong Choi ,  Sung Kyun Han

IPC分类号： A61K31/4725 ,  A61K31/439 ,  A61K47/10 ,  A61K47/38 ,  A61K9/20

CPC分类号： A61K31/4725 ,  A61K9/2054 ,  A61K9/2095 ,  A61K31/439 ,  A61K47/10 ,  A61K47/38

摘要： The present invention relates to a solifenacin preparation containing solifenacin or a pharmaceutically acceptable salt thereof, an antioxidant, and a binder, which is manufactured via direct compression. Compared to the preparations manufactured via conventional wet granulation process, the preparation of the present invention can be manufactured by a simplified process such as direct compression, and has improved content uniformity, mixing degree, etc., even when the preparation is manufactured by high speed tableting.

公开(公告)号：US10047041B2

公开(公告)日：2018-08-14

申请号：US15506211

申请日：2015-07-14

申请人： CJ Healthcare Corporation

发明人： Jae Ho Yoo ,  Seung Chan Kim ,  Soo Yeon Jung ,  Hyoung Rok Bak ,  Young Mee Chung ,  Sung Jun Kim ,  Sook Kyung Park ,  Seog Beom Song ,  Shin-Young Ryu ,  Mi Young Yoon ,  Dong Hyun Ko ,  Sun Young Park ,  Chi Hye Park ,  Nak Hyun Choi

IPC分类号： C07C317/14 ,  C07D307/79 ,  C07D307/52 ,  C07D213/36 ,  C07D317/46 ,  C07D319/16

CPC分类号： C07C317/14 ,  A61K31/192 ,  A61K31/196 ,  A61K31/341 ,  A61K31/343 ,  A61K31/357 ,  A61K31/36 ,  A61K31/44 ,  A61K31/4406 ,  A61K31/4409 ,  C07C317/44 ,  C07C2603/26 ,  C07D213/36 ,  C07D213/64 ,  C07D307/52 ,  C07D307/79 ,  C07D307/81 ,  C07D317/46 ,  C07D317/58 ,  C07D317/62 ,  C07D319/16 ,  C07D319/18

摘要： The present invention relates to a novel amino-phenyl-sulfonyl-acetate derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating diabetes comprising the same as an active ingredient.

公开(公告)号：US20170247320A1

公开(公告)日：2017-08-31

申请号：US15506211

申请日：2015-07-14

申请人： CJ Healthcare Corporation

发明人： Jae Ho Yoo ,  Seung Chan Kim ,  Soo Yeon Jung ,  Hyoung Rok Bak ,  Young Mee Chung ,  Sung Jun Kim ,  Sook Kyung Park ,  Seog Beom Song ,  Shin-Young Ryu ,  Mi Young Yoon ,  Dong Hyun Ko ,  Sun Young Park ,  Chi Hye Park ,  Nak Hyun Choi

IPC分类号： C07C317/14 ,  C07D319/16 ,  C07D213/36 ,  C07D317/46 ,  C07D307/79 ,  C07D307/52

CPC分类号： C07C317/14 ,  A61K31/192 ,  A61K31/196 ,  A61K31/341 ,  A61K31/343 ,  A61K31/357 ,  A61K31/36 ,  A61K31/44 ,  A61K31/4406 ,  A61K31/4409 ,  C07C317/44 ,  C07C2603/26 ,  C07D213/36 ,  C07D213/64 ,  C07D307/52 ,  C07D307/79 ,  C07D307/81 ,  C07D317/46 ,  C07D317/58 ,  C07D317/62 ,  C07D319/16 ,  C07D319/18

摘要： The present invention relates to a novel amino-phenyl-sulfonyl-acetate derivative or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating diabetes comprising the same as an active ingredient.

公开(公告)号：US20150216856A1

公开(公告)日：2015-08-06

申请号：US14608560

申请日：2015-01-29

申请人： CJ HEALTHCARE CORPORATION

发明人： Young Hee Suh ,  Young Dae Cho ,  Chun Seon Lyu ,  Mi Young Yoon ,  Ha Yong Choi ,  Sung Kyun Han

IPC分类号： A61K31/4725 ,  A61K47/10 ,  A61K9/20 ,  A61K47/38

CPC分类号： A61K31/4725 ,  A61K9/2054 ,  A61K9/2095 ,  A61K31/439 ,  A61K47/10 ,  A61K47/38

摘要： The present invention relates to a solifenacin preparation containing solifenacin or a pharmaceutically acceptable salt thereof, an antioxidant, and a binder, which is manufactured via direct compression. Compared to the preparations manufactured via conventional wet granulation process, the preparation of the present invention can be manufactured by a simplified process such as direct compression, and has improved content uniformity, mixing degree, etc., even when the preparation is manufactured by high speed tableting.

摘要翻译： 本发明涉及通过直接压片制造的含有索非那新或其药学上可接受的盐，抗氧化剂和粘合剂的索利那新制剂。 与通过常规湿式造粒法制备的制剂相比，本发明的制备方法可以通过简单的方法制造，例如直接压制，并且具有改善的含量均匀性，混合度等，即使制备高速制造 压片