公开(公告)号：US20190201812A1

公开(公告)日：2019-07-04

申请号：US16311750

申请日：2017-06-20

Applicant: CLEMSON UNIVERSITY

Inventor： R. Kenneth MARCUS ,  LIUWEI JIANG

IPC: B01D15/20 ,  B01J20/26 ,  B01J20/286 ,  B01J20/32 ,  B01J20/30 ,  B01J20/28

CPC classification number: B01D15/20 ,  B01D15/22 ,  B01D15/305 ,  B01D15/361 ,  B01D15/3804 ,  B01D63/02 ,  B01D67/0093 ,  B01D69/082 ,  B01D71/56 ,  B01D2323/38 ,  B01J20/264 ,  B01J20/28023 ,  B01J20/286 ,  B01J20/3078 ,  B01J20/3212 ,  B01J20/3278 ,  B01J20/328 ,  B01J39/26 ,  B01J41/20 ,  B01J47/127 ,  B01J2220/58 ,  G01N33/68

Abstract: Chromatography devices and methods for forming and using the devices are described. The devices include a polyimide-based support phase and a polymer grafted to a surface of the polyimide-based support phase. A microwave-assisted graft polymerization protocol is described to form the polymer at the surface of the support phase. Devices can be utilized in high-efficiency separation of macromolecules such as proteins.