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公开(公告)号：US11464670B2
公开(公告)日：2022-10-11
申请号：US16332630
申请日：2017-09-12
申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES , UNIVERSITE GRENOBLE ALPES , CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES
摘要： The invention relates to a device for cooling an organ locally, that includes an elongate stem including a far end intended to make contact with an organ to be cooled and comprising including a cooling element having a cold finger, a crystal that has a capacity to cool via excitation at a set excitation wavelength, said crystal being positioned adjacent to said cooling element, an optical guide that is able to convey a light signal at said excitation wavelength and that opens onto said crystal, and an illuminating system including at least one light source, which light source is arranged to emit said light signal.
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公开(公告)号：US20210016111A1
公开(公告)日：2021-01-21
申请号：US17040233
申请日：2019-03-19
申请人： Boston Scientific Neuromodulation Corporation , COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES ("CEA")
发明人： Dennis Allen Vansickle , Adam Thomas Featherstone , Claude Chabrol , Michael A. Moffitt , Sarah Renault , Adrien Poizat
摘要： An optical stimulation system includes a light source; an optical lead coupled, or coupleable, to the light source; at least one of a calibration table or a calibration formula, generated by a calibration procedure specifically using the light source and the optical lead of the optical stimulation system; and a control unit coupled, or coupleable, to the light source. The control module includes a memory to store the at least one of the calibration table or the calibration formula, and a processor coupled to the memory and configured for receiving a target light output level, using the at least one of the calibration table or the calibration formula to determine at least one operational parameter for generating the target light output level, and directing the light source, using the at least one operational parameter, to generate light at the target light output level.
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公开(公告)号：US11648416B2
公开(公告)日：2023-05-16
申请号：US17117318
申请日：2020-12-10
发明人： Claude Chabrol
IPC分类号： A61N5/06
CPC分类号： A61N5/0622 , A61N2005/0632 , A61N2005/0651 , A61N2005/0664
摘要： An optically stimulating module to be integrated into a probe is implantable into a living being with a view to locally illuminating a region of said living being. The module includes a casing, and a hermetic electronic unit housed in the casing. The hermetic electronic unit includes two luminous diodes connected back-to-back, and at least two electrical contacts for connecting the module to an electrical power source.
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公开(公告)号：US11600962B2
公开(公告)日：2023-03-07
申请号：US16774131
申请日：2020-01-28
摘要： A device for cooling locally, including a cooling member, a crystal having the capacity to cool via absorption of a near-infrared exciting light signal, an illuminating system intended to deliver an exciting light signal, the crystal having an elongate shape about a longitudinal axis between a near end and a far end and having a closed constant outside cross section and containing a central channel formed, from its far end, over at least some of its length, the cooling member including a rod embedded via a first end into the central channel of the crystal and including a protruding second end that forms a cooling finger.
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公开(公告)号：US12011610B2
公开(公告)日：2024-06-18
申请号：US17117855
申请日：2020-12-10
发明人： Claude Chabrol , Patrice Caillat
IPC分类号： A61N5/06
CPC分类号： A61N5/0601 , A61N5/0618 , A61N5/0622 , A61N2005/0628 , A61N2005/0632
摘要： An optically stimulating module to be integrated into a probe is implantable into a living being with a view to locally illuminating a region of said living being. The module includes a casing that is at least partially transparent, and a hermetic electronic unit placed in the casing. The hermetic electronic unit includes an internal volume housing two light sources, a control and processing unit, and a first photodetector. The module also includes a connecting device for connecting the module to a central control and power unit.
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公开(公告)号：US11541248B2
公开(公告)日：2023-01-03
申请号：US16771464
申请日：2018-12-03
发明人： Claude Chabrol , Sarah Renault
IPC分类号： A61N5/06
摘要： The invention relates to an implantable illuminating device intended to be implanted in a living being with a view to locally illuminating a region of said living being, said device including a probe, said architecture being characterized in that it is produced from: an optical fiber that comprises a core, a cladding and a protective coating, a jacket, said architecture including: a plurality of successive segments along its longitudinal axis, each segment having a section containing a plurality of concentrically superposed layers, in which each segment includes a section containing a plurality of superposed layers that is different from the section of each adjacent segment.
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公开(公告)号：US10702697B2
公开(公告)日：2020-07-07
申请号：US15575191
申请日：2016-05-12
发明人： Claude Chabrol , Alim-Louis Benabid
摘要： A deep brain stimulation device includes a probe having a transparent distal portion, crossed by a channel open at a proximal end of the probe, and also includes electrodes affixed to the distal portion of the probe and electrode terminals affixed to a proximal portion of the probe. Further, the device includes an electrical housing including a channel open at its two ends and housing electrical terminals in contact with the terminals of the probe, and an electrical extension lead affixed to the housing and connected to the terminals of the housing. The channel of the housing is open at the other one of its ends and the device further includes a waveguide at least partly housed in the central channel of the probe, all the way to the distal portion of the probe, and a transmitter housing capable of being connected to the waveguide for the injection of a predetermined wavelength.
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公开(公告)号：US11565131B2
公开(公告)日：2023-01-31
申请号：US17040233
申请日：2019-03-19
申请人： Boston Scientific Neuromodulation Corporation , COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (“CEA”)
发明人： Dennis Allen Vansickle , Adam Thomas Featherstone , Claude Chabrol , Michael A. Moffitt , Sarah Renault , Adrien Poizat
摘要： An optical stimulation system includes a light source; an optical lead coupled, or coupleable, to the light source; at least one of a calibration table or a calibration formula, generated by a calibration procedure specifically using the light source and the optical lead of the optical stimulation system; and a control unit coupled, or coupleable, to the light source. The control module includes a memory to store the at least one of the calibration table or the calibration formula, and a processor coupled to the memory and configured for receiving a target light output level, using the at least one of the calibration table or the calibration formula to determine at least one operational parameter for generating the target light output level, and directing the light source, using the at least one operational parameter, to generate light at the target light output level.
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公开(公告)号：US20180154152A1
公开(公告)日：2018-06-07
申请号：US15575191
申请日：2016-05-12
发明人： Claude Chabrol , Alim-Louis Benabid
摘要： A deep brain stimulation device including: a probe (60) having a transparent distal portion, crossed by a channel (28) open at a proximal end of the probe, and including electrodes (20a, 20b, 20c, 20d) affixed to the distal portion of the probe and electrode terminals (22a, 22b, 22c, 22d) affixed to a proximal portion of the probe; an electrical housing including a channel open at its two ends and housing electrical terminals in contact with the terminals (22a, 22b, 22c, 22d) of the probe; and an electrical extension lead affixed to the housing and connected to the terminals of the housing. The channel of the housing is open at the other one of its ends and the device further includes: a waveguide (50) at least partly housed in the central channel (28) of the probe, all the way to the distal portion of the probe; and a transmitter housing capable of being connected to the waveguide (50) for the injection of a predetermined wavelength.
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